Amprenavir - Wikipedia
Amprenavir (original brand name Agenerase, GlaxoSmithKline) is a protease inhibitor used to treat HIV infection. It was approved by the Food and Drug Administration on April 15, 1999, for twice-a-day dosing instead of needing to be taken every eight hours.
Amprenavir: Uses, Interactions, Mechanism of Action - DrugBank …
Amprenavir is a protease inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Protease inhibitors block the part of HIV called protease. HIV-1 protease is an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1.
amprenavir, Agenerase: Drug Facts, Side Effects and Dosing - MedicineNet
Amprenavir is an oral medication that is used for treating infections with the human immunodeficiency virus (HIV). It is in a class of drugs called protease inhibitors which, among others, includes indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir) and saquinavir (Invirase, Fortovase).
DESCRIPTION: AGENERASE (amprenavir) is an inhibitor of the human immunodeficiency virus (HIV) protease. The chemical name of amprenavir is (3S)-tetrahydro-3-furyl...
Amprenavir - an overview | ScienceDirect Topics
Amprenavir is an HIV protease inhibitor with an enzyme inhibitory constant of 0.6 nmol/l, similar to the inhibitory constants of other protease inhibitors. Its in vitro IC50 against wild-type clinical HIV isolates is 115 ng/ml. It has a long half-life (7–10 hours).
Amprenavir: A new human immunodeficiency virus type 1 protease ...
2000年5月1日 · Amprenavir, the most recent HIV-1 protease inhibitor to receive marketing approval from the US Food and Drug Administration, is a potent competitive inhibitor of HIV-1 protease and a relatively weak inhibitor of HIV-2 protease.
Pharmacology and clinical experience with amprenavir
Amprenavir (APV, Agenerase) is the fifth protease inhibitor (PI) available for clinical use. It is highly active and its pharmacokinetics allow convenient twice-daily administration. It is metabolised by the cytochrome P450 system, leading to a number of drug interactions that have been well defined …
Amprenavir Dosage Guide + Max Dose, Adjustments - Drugs.com
Detailed Amprenavir dosage information for adults and children. Includes dosages for HIV Infection; plus renal, liver and dialysis adjustments.
Amprenavir | C25H35N3O6S | CID 65016 - PubChem
Amprenavir is a human immunodeficiency virus (HIV)-protease inhibitor. The use of amprenavir for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in combination with other antiretrovirals is based on analyses of plasma HIV-RNA levels and CD4 cell counts in controlled studies of up to 24 weeks duration.
AGENERASE (amprenavir) is an inhibitor of the human immunodeficiency virus (HIV) protease. The chemical name of amprenavir is (3S)-tetrahydro-3-furyl...