Louisville [b] is the most populous city in the Commonwealth of Kentucky, sixth-most populous city in the Southeast, and the 27th-most-populous city in the United States. [a] [11] By land area, it is the country's 24th-largest city, although by population density, it is the 265th most dense city.[c] [12] Louisville is the historical county seat and, since 2003, the nominal seat of Jefferson ...