Plasma cell dyscrasias - Wikipedia
In hematology, plasma cell dyscrasias (also termed plasma cell disorders and plasma cell proliferative diseases) are a spectrum of progressively more severe monoclonal gammopathies in which a clone or multiple clones of pre-malignant or malignant plasma cells (sometimes in association with lymphoplasmacytoid cells or B lymphocytes) over-produce ...
Blood Dyscrasias: Symptoms, Causes, and Treatment - Verywell …
2023年9月7日 · Blood dyscrasias are disorders affecting blood cells, plasma proteins, and more. Learn about the types, symptoms, causes, diagnosis, and treatment.
Plasma Cell Dyscrasia - an overview | ScienceDirect Topics
Plasma cell dyscrasias are a heterogeneous group of disorders caused by the monoclonal proliferation of lymphoplasmacytic cells in the bone marrow. Multiple myeloma is the most serious and prevalent plasma cell dyscrasia, with a median age of onset of 60 years.
Plasma Cell Dyscrasias | Choose the Right Test - ARUP Consult
Plasma cell dyscrasia evaluation begins with an investigation of the presence and type of monoclonal proteins (also known as M proteins). Serum free light chain (SFLC) quantification aids in diagnosing multiple myeloma and determining prognosis.
Overview of Plasma Cell Disorders - The Merck Manuals
Plasma cell disorders may be suspected because of clinical manifestations, most often bone disease, renal failure, and low blood counts, or an incidental finding of elevated serum protein or proteinuria that leads to further evaluation with serum or urine protein electrophoresis.
What Is Plasma Cell Dyscrasias? - iCliniq
2024年2月9日 · Plasma cell dyscrasia refers to a group of disorders characterized by the abnormal proliferation of plasma cells in the bone marrow. This can lead to multiple myeloma or plasma cell leukemia , which can cause symptoms such as bone pain, weakness, fatigue , and frequent infections.
Overview of Plasma Cell Disorders - The Merck Manuals
Plasma cell disorders are uncommon. They begin when a single plasma cell multiplies excessively. The resulting group of genetically identical cells (called a clone) produces a large quantity of a single type of antibody (immunoglobulin). Plasma cells develop from B cells (B lymphocytes), a type of white blood cell that normally produces antibodies.
Plasma Cell Dyscrasia - an overview | ScienceDirect Topics
Plasma cell dyscrasias are HCs of plasma cells, the terminally differentiated B cells that secrete antibody in response to antigen. Normal plasma cells cannot divide and so die after doing their job of secreting antibody for a few days.
Plasma Cell Dyscrasia: Definition, Classification, Diagnosis
Plasma cell dyscrasia is a medical condition, in which the plasma cells are affected. The abnormal proliferation of the plasma cells leads to the appearance of plasma cell dyscrasia, with the monoclonal population of cells secreting immunoglobulin or fragments of immunoglobulin (these fragments are known as paraprotein or M protein ).
Multiple Myeloma and Other Plasma Cell Dyscrasias - Cancer …
2016年6月1日 · This management guide covers the symptoms, diagnosis, screening, staging, and treatment of multiple myeloma, smoldering myeloma, and other plasma cell dyscrasias.
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