Uridine Diphosphate Galactose - an overview - ScienceDirect
Uridine Diphosphate Galactose (UDP galactose) is a type of UDP-sugar that functions as an extracellular signaling molecule during cell injury and apoptosis, playing a role in regulating immune responses and promoting inflammation through specific receptor pathways.
Galactose-uridine-5'-diphosphate | C15H24N2O17P2 - PubChem
It is a conjugate acid of an UDP-alpha-D-galactose (2-). A nucleoside diphosphate sugar which can be epimerized into UDPglucose for entry into the mainstream of carbohydrate metabolism. Serves as a source of galactose in the synthesis of lipopolysaccharides, cerebrosides, and …
Epimerase Deficiency Galactosemia - GeneReviews® - NCBI Bookshelf
2011年1月25日 · Persons with epimerase deficiency galactosemia who are exposed to galactose demonstrate abnormal accumulation of UDP-galactose (UDP-gal).
UDP-Galactose 4′-Epimerase Activities toward UDP-Gal and UDP …
In both humans and Drosophila melanogaster, UDP-galactose 4′-epimerase (GALE) catalyzes two distinct reactions, interconverting UDP-galactose (UDP-gal) and UDP-glucose (UDP-glc) in the final step of the Leloir pathway of galactose metabolism, and also interconverting UDP-N-acetylgalactosamine (UDP-galNAc) and UDP-N-acetylglucosamine (UDP ...
The Uridine diphosphate (UDP)-glycosyltransferases (UGTs) …
UDP-glucose is an important branch point of sugar metabolism. It can be used for the synthesis of UDP-glucuronide, UDP-galactose, and also as an entry point for polysaccharide synthesis. UDP-glucose is catalyzed by UDP-glucose dehydrogenase (UGDH) to produce UDP-glucuronide.
Uridine Diphosphate Galactose - an overview - ScienceDirect
Galactose-1-phosphate is exchanged for the glucose-1-phosphate moiety of uridine diphosphate glucose (UDPG) to form uridine diphosphate galactose (UDPGal) by galactose-1-phosphate uridyl transferase (transferase or GALT). The glucose-1-phosphate …
One-pot three-enzyme synthesis of UDP-Glc, UDP-Gal, and …
2013年5月24日 · A UTP-glucose-1-phosphate uridylyltransferase (GalUSpe4) and a galactokinase (GalKSpe4) were cloned from Streptococcus pneumoniae TIGR4 and were successfully used to synthesize UDP-galactose (UDP-Gal), UDP-glucose (UDP-Glc), and their derivatives in an efficient one-pot reaction system.
UDP-galactose | C15H24N2O17P2 | CID 23724458 - PubChem
UDP-galactose | C15H24N2O17P2 | CID 23724458 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Gene regulation of UDP-galactose synthesis and transport: potential ...
2012年8月1日 · In summary, we have demonstrated that genes controlling conversion of glucose to UDP-galactose (UGP2 and PGM1) and UDP-galactose transport into the Golgi (SLC35A2) may be rate limiting in the lactose synthesis.
A systematic review of the Uridine diphosphate-Galactose
2021年1月6日 · Uridine diphosphate (UDP)-Galactose/Glucose-4-epimerase (UGE) is the third enzyme involved in the Leloir pathway. It catalyzes the conversion of UDP-Galactose to UDP-Glucose, which is a rate-limiting step for polysaccharides biosynthesis.
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