Th1 and Th2 responses: what are they? - PMC
The Th2-type cytokines include interleukins 4, 5, and 13, which are associated with the promotion of IgE and eosinophilic responses in atopy, and also interleukin-10, which has more of an anti-inflammatory response. In excess, Th2 responses will counteract the …
T helper cell - Wikipedia
During an immune response, professional antigen-presenting cells (APCs) endocytose antigens (typically bacteria or viruses), which undergo processing, then travel from the infection site to the lymph nodes. Typically, the APC responsible is a dendritic cell.
Th1 and Th2 responses: what are they? - The BMJ
2000年8月12日 · The Th2-type cytokines include interleukins 4, 5, and 13, which are associated with the promotion of IgE and eosinophilic responses in atopy, and also interleukin-10, which has more of an anti-inflammatory response. In excess, Th2 responses will counteract the Th1 mediated microbicidal action.
TH2 cell development and function | Nature Reviews Immunology
2017年10月30日 · T helper 2 (TH2) cells orchestrate protective type 2 immune responses, such as those that target helminths and facilitate tissue repair, but also contribute to chronic inflammatory diseases,...
Recent advances in understanding the Th1/Th2 effector choice
In this review, we will discuss some recent interesting advances towards understanding the Th1/Th2 effector cell “choice”, particularly during in vivo immune responses, which include the role of new players in the transcriptional network, the contributions of dendritic cells (DCs) and innate lymphoid cells (ILCs) in the initiation of T cell ...
Current understanding of Th2 cell differentiation and function
The type 2 helper Tcell (Th2), characterized by the production of interleukin-4 (IL-4), IL-5 and IL-13, plays a critical role in immune response against helminths invading cutaneous or mucosal sites. It also has a functional role in the pathophysiology of allergic diseases such as asthma and allergic diarrhea.
How are TH2-type immune responses initiated and amplified ...
CD4+ T helper (TH) cells have crucial roles in orchestrating adaptive immune responses. TH2 cells control immunity to extracellular parasites and all forms of allergic inflammatory responses.