Plasma testosterone levels in C57BL/6J male mice: effects of ... - PubMed
Plasma testosterone (T) was measured by radioimmunoassay in both healthy and diseased, mature (8-11 months) and senescent (29-31 months) C57BL/6J male mice. Pathological lesions in diseased mice included reticulum cell sarcoma and enlarged mesenteric lymph nodes.
Plasma Testosterone Levels in C57Bl/6J Male Mice ... - Oxford …
Dec 1, 1975 · Plasma testosterone (T) was measured by radioimmunoassay in both healthy and diseased, mature (8–11 months) and senescent (29–31 months) C57BL/6J male mice. Pathological lesions in diseased mice included reticulum cell …
Analysis of testosterone and dihydrotestosterone in mouse …
A novel method was established for simultaneous quantitation of testosterone (T) and dihydrotestosterone (DHT) in murine tissue and serum samples. Endogenous T and DHT, together with the internal standards, 17α-methyl-T and 17α-methyl-DHT, were ...
Measurement of Testosterone by Immunoassays and Mass …
Jan 1, 2015 · Testosterone was measured in serum and extracts of testis or ovary from male and female wild-type mice by 2 commercial direct testosterone immunoassays, with and without preassay extraction, and by the liquid chromatography, tandem mass …
Signs of diastolic dysfunction are graded by serum testosterone levels ...
Sep 1, 2021 · We investigated whether maladaptive, age-associated changes in heart structure and function were linked to circulating testosterone levels. Male C57BL/6 mice had a gonadectomy (GDX) or sham surgery at 4 weeks and effects of GDX on the heart were examined with echocardiography. Serum testosterone was measured with ELISA.
血清睾酮浓度与自然衰老和睾酮缺乏的老年 C57Bl/6 小鼠的虚弱无 …
Frailty scores (31-item frailty index) and testosterone were measured between 18- to 24-months of age. Age predicted frailty (p < 0.0001), but serum testosterone did not (p = 0.357). Life expectancy (AFRAID clock) and biologic age (FRIGHT clock) were not significantly different between groups (p = 0.485 and 0.142).
Plasma testosterone levels in C57BL/6J male mice: effects of
Plasma testosterone (T) was measured by radioimmunoassay in both healthy and diseased, mature (8 to 11 months) and senescent (29 to 31 months) C57BL/6J male mice. Pathological lesions in diseased mice included reticulum cell sarcoma and enlarged mesenteric lymph nodes.
How Estrogen, Testosterone, and Sex Differences Influence Serum ...
Feb 9, 2023 · To help explain these differences, we first studied serum immunoglobulin isotype patterns in C57BL/6 male and female mice. We focused on IgG2b, an isotype that lends to virus control and that has been previously shown to be elevated in murine females compared to males.
Serum testosterone concentrations are not associated with frailty …
Apr 1, 2022 · This study investigated how serum testosterone related to frailty in ageing male C57Bl/6 mice with or without lifelong testosterone deficiency. Mice underwent a sham surgery (n = 10) or gonadectomy (n = 11, GDX) at 4-weeks and then aged. Frailty scores (31-item frailty index) and testosterone were measured between 18- to 24-months of age.
Clinical and Laboratory Standards Institute document C57—Mass Spectrometry for Androgen and Estrogen Measurements in Serum is intended to aid the laboratorian in developing appropriate procedures for the use of mass spectrometry (MS) in the measurement of …