Ophthalmologic Manifestations of Syphilis - EyeWiki
Acute syphilitic posterior placoid chorioretinitis (ASPPC) is a rare manifestation of ocular syphilis that has been described in patients with secondary syphilis. ASPPC lesions are located on the surface of the retina (retinal pigmented epithelium, RPE) at or near the macula.
Diagnosis and Management of Ocular Syphilis
May 1, 2023 · One essentially pathognomonic manifestation of posterior involvement is known as acute posterior placoid chorioretinopathy, which affects the retinal pigment epithelium (Fig. 3). Secondary syphilis may last as long as two years.
Ocular Syphilis With Phlebitis and Paravenous Pigmentary Retinopathy
Oct 24, 2021 · Ocular syphilis with a resulting atrophic pigmentary retinopathy is an even more atypical outcome after treatment. We present the case of a patient newly diagnosed with HIV and ocular syphilis who presented with predominantly venous involvement and a dramatic progression, despite treatment, to a paravenous pigmentary retinopathy.
Ocular Syphilis on the Rise: Review of Diagnostics and Management
Mar 7, 2024 · Syphilis may be seen in four stages—primary, secondary, latent, and tertiary—depending on the physical spread of the disease. The primary stage is characterized by a painless chancre sore at the site of infection—usually the genitals, anus, or mouth. If not treated, the disease progresses to the secondary stage after weeks to months.
Syphilis Ocular Manifestations - StatPearls - NCBI Bookshelf
Aug 25, 2023 · Syphilis can involve almost any ocular structure, but posterior uveitis and panuveitis are the most common presentations. Other common manifestations include interstitial keratitis, recurrent anterior uveitis, retinal vasculitis, and optic neuropathy. [2] . Ocular syphilis, if untreated, may lead to blindness.
Persistent syphilitic ocular manifestations despite treatment: a case ...
Management of ocular syphilis is challenging despite the efficacy of treatment with penicillin. In our case series, we documented three syphilis cases with persistent retinal manifestations despite following standard of care. These cases demonstrated chronic inflammation, incomplete treatment, and reinfection as contributors to the persistence.
Ocular Syphilis With Phlebitis and Paravenous Pigmentary Retinopathy
Oct 24, 2021 · Purpose: Ocular syphilis can present as a wide variety of clinical phenotypes, among them panuveitis with vasculitis. Primary retinal phlebitis with resulting paravenous atrophy and pigmentary retinal degeneration is a rare presentation. Methods: A 53-year-old man presented with a 1-year history of bilateral blurry vision. Physical examination ...
Ocular Syphilis With Phlebitis and Paravenous Pigmentary Retinopathy ...
Oct 24, 2021 · Ocular syphilis can present as a wide variety of clinical phenotypes, among them panuveitis with vasculitis. Primary retinal phlebitis with resulting paravenous atrophy and pigmentary retinal degeneration is a rare presentation. A 53-year-old man presented with a 1-year history of bilateral blurry vision.
Pyramidal Inflammatory Deposits of the Retinal Pigment …
After observing a relatively high frequency of inflammatory deposits in the retinal pigment epithelium (RPE) and outer retina in syphilitic posterior uveitis, we aimed to characterize these lesions better in this study and hypothesized that their identification could serve as an additional characteristic clinical finding for the disease.
Syphilis - SpringerLink
Dec 22, 2018 · Pigmentary retinopathy can occur in both congenital and acquired syphilis and may mimic advanced retinitis pigmentosa. Pigmentary changes are usually in clumps, along with chorioretinal scars; typical bony-spicule pigmentation is uncommon. Therefore, syphilis can masquerade retinitis pigmentosa (Pseudoretinitis pigmentosa).