Injection-Site Reactions and How to Manage Them - Pharmacy Times
Nov 19, 2019 · Typically, an injection-site reaction is considered to be any pain, swelling, rash, bleeding, or redness that occurs at the site of an injection, although, serious reactions can occur (see sidebar 1). 2 A small amount of pain or redness is expected with an intramuscular (IM) or subcutaneous injection, and a warning to this effect is included in ...
Subcutaneous Injections: Where and How To Give
Sep 20, 2023 · How to give yourself a subcutaneous injection. You may experience minor pain or bruising at the injection site, but your chances of discomfort lessen if you inject the medication correctly.
Injection site reactions: Types, causes, treatment, and more
Apr 3, 2024 · Any injection can cause an injection site reaction if the immune system responds to the skin injury or the substance in the injection. Symptoms often include skin redness and discoloration ...
Injection Side Effects and When to Seek Medical Help - Verywell …
Jul 27, 2023 · Injection site reactions are common after vaccines or treatments delivered through a shot. These may include a little swelling, tenderness, pain, itching, or redness around the area where the injection was given. Typically, any minor discomfort goes away in one or two days.
Injection Site Reactions: Symptoms, Treatment, and Prevention - GoodRx
Aug 5, 2024 · Injection site reactions can happen if something in the injection: Irritant reactions are more common after subcutaneous injections. They tend to develop quickly — usually within a couple of hours. Immune-mediated reactions can happen fast too, but more often they take a few days to develop.
Reducing Intramuscular and Subcutaneous Injection Pain
Feb 24, 2022 · To reduce the pain and fear associated with regular injections, try numbing the injection site with ice and/or a numbing cream. Talk with your healthcare provider about the best sites for intramuscular or subcutaneous injections, and rotate the injection site if …
Towards more tolerable subcutaneous administration: Review of ...
Jun 1, 2024 · Subcutaneous (SC) injections can be associated with local pain and discomfort. Multiple intertwined factors contribute to SC injection site pain/discomfort. Device, delivery, and formulation factors influencing injection pain are reviewed. Emotional/psychological aspects impacting pain perception are discussed.
Understanding and Minimising Injection-Site Pain Following Subcutaneous …
Nov 18, 2020 · Injection-site pain (ISP) is a commonly reported subjective side effect with the subcutaneous (SC) administration of biological agents, yet it may only be a concern to some. Multiple factors, including those related to product formulation (e.g. pH, volume, excipients, injection process) and to the patient (low body weight, gender and age) have ...
Subcutaneous Injection of Drugs: Literature Review of Factors ...
Oct 5, 2019 · Short and thin needles, conveniently lubricated and with sharp tips, are generally used to minimize pain, although the anatomic injection site (abdomen versus thigh) also affects the sensation of pain. Large subcutaneous injection volumes are associated with pain.
Injection site reactions after subcutaneous oligonucleotide therapy
When administered subcutaneously (sc), ONs cause a specific local reaction originating around the injection site, such as erythema, itching, discomfort and pain, including more severe manifestations such as ulceration or necrosis. These injection site reactions (ISRs) are common, but rather poorly described in the literature.