Stem cell factor - Wikipedia
Stem cell factor (also known as SCF, KIT-ligand, KL, or steel factor) is a cytokine that binds to the c-KIT receptor (CD117). SCF can exist both as a transmembrane protein and a soluble protein. This cytokine plays an important role in hematopoiesis (formation of blood cells), spermatogenesis, and melanogenesis.
干细胞生长因子 - 百度百科
干细胞生长因子（Stem Cell Growth Factors）是美国AgingOff Biotech,Inc.联合哈弗大学、宾夕法尼亚大学、匹兹堡大学、麻省理工大学等机构共同开放的一种具有刺激自体内源性干细胞生长的高效蛋白质、酶组合，也是体外培养干细胞必不可少的各种细胞生长因子的组合 ...
重组人干细胞因子SCF新近发现的重要造血细胞因子 - 知乎
英文名字： Recombinant Human Stem Cell Factor. INCI：Sh-Polypeptide-4 ; Rh-Polypeptide-4. 来源：酵母. 分子量：约为16.0-26.0kD 糖基化蛋白. 规格：10微克、 100微克. 产品介绍：
Stem cell factor receptor/c-Kit: from basic science to clinical ...
Stem cell factor (SCF) is a dimeric molecule that exerts its biological functions by binding to and activating the receptor tyrosine kinase c-Kit. Activation of c-Kit leads to its autophosphorylation and initiation of signal transduction.
Stem Cell Factor - an overview | ScienceDirect Topics
Stem cell factor (SCF), the ligand of the c-Kit receptor, is expressed by various structural and inflammatory cells in the airways. Binding of SCF to c-Kit leads to activation of multiple pathways, including phosphatidyl-inositol-3 (PI3)-kinase, phospholipase C (PLC)-γ, Src kinase, Janus kinase (JAK)/Signal Transducers and Activators of ...
干细胞因子 | Stem cell factor (SCF) | MCE - MCE-生物活性分子 ...
Stem cell factor (SCF) is a dimeric molecule that exerts its biological functions by binding to and activating the receptor tyrosine kinase c-Kit. Signaling from c-Kit is crucial for normal hematopoiesis, pigmentation, fertility, gut movement, and some aspects of the nervous system.
Stem Cell Factor - an overview | ScienceDirect Topics
Stem cell factor, also known as the "steel factor", is a cytokine that is secreted by a number of cells and it acts by binding to c-kit, a tyrosine kinase receptor expressed in all types of hematopoietic stem cells.
Stem cell factor - Holland-Frei Cancer Medicine - NCBI Bookshelf
Stem cell factor (SCF) is also known as kit ligand, mast cell growth factor, or steel factor. It functions as a hematopoietic cytokine that triggers its biologic effect by binding to c-kit (the SCF receptor) (Table 58-7).27
The stem cell factor/Kit signalling pathway regulates ... - Nature
2014年7月7日 · Receptor tyrosine kinase Kit and its ligand, stem cell factor (SCF), play a critical role in the growth and survival of multiple cell lineages. Here we report that the expression of SCF and Kit...
Tissue Distribution of Stem Cell Factor in Adults - PMC
Stem cell factor (SCF) is an essential cytokine during development and is necessary for gametogenesis, hematopoiesis, mast cell development, stem cell function, and melanogenesis. Here, we measure SCF concentration and distribution in adult humans and mice using gene expression analysis, tissue staining, and organ protein lysates.