Skin-on-a-chip models: General overview and future perspectives
2021年7月8日 · Advances in vascularized human skin equivalents (HSEs), transferred skin-on-a-chip (introduction of a skin biopsy or a HSE in the chip), and in situ skin-on-a-chip (generation of the skin model directly in the chip) are critically reviewed, and currently used methods for the introduction of skin cells in the microfluidic chips are discussed. An ...
Design and evaluation of a skin-on-a-chip pumpless ... - Nature
2023年5月31日 · A novel skin-on-chip device was introduced with an innovative microfluidic design that enabled the maintenance of normal skin tissue for a long time without using any support materials.
Advances in Skin-on-a-Chip Technologies for Dermatological …
2024年8月1日 · Skin-on-a-chip (SoC) technologies are emerging as a paradigm shift in dermatology research by replicating human physiology in a dynamic manner not achievable by current animal models.
Skin-on-a-chip model simulating inflammation, edema and drug …
2016年11月21日 · In this paper, we describe the development of ‘skin-on-a-chip’ to mimic the structures and functional responses of the human skin. The proposed model consists of 3 layers, on which...
Advances in skin-on-a-chip and skin tissue engineering
2023年1月1日 · In this chapter, we present an overview of the current state-of-the-art in tissue-engineered skin and skin-on-a-chip technologies. These advanced systems can be used to recapitulate the physiology of healthy and diseased human skin, and to carry out pharmacokinetic/pharmacodynamic studies.
Current advances in skin-on-a-chip models for drug testing
2018年8月1日 · “Skin-on-a-chip” is to culture skin tissues within a microfluidic system, which can control many physical and biochemical parameters such as medium flow, mechanical force and gradients of biochemicals, mimicking the 3D microenvironments of the natural human skin.
Skin-on-a-chip models: General overview and future perspectives
2021年5月19日 · Advances in vascularized human skin equivalents (HSEs), transferred skin-on-a-chip (introduction of a skin biopsy or a HSE in the chip), and in situ skin-on-a-chip (generation of the...
Skin-on-Chip - SpringerLink
Skin-on-Chip (SOC) model includes culturing skin tissues with the microfluidic system incorporated within it. Dynamic SOC models have been developed to reflect the mechanical stress conditions faced by the cells and perfusion systems to maintain the cultures for a …
Progress and Future Prospectives in Skin-on-Chip Development …
Skin-on-chip and induced pluripotent stem cells (iPSC) might be key technologies to improve in vitro skin models. This review summarizes the state of the art of in vitro skin models with regard to cell sources (primary, cell line, iPSC) and microfluidic devices.
3D skin models along with skin-on-a-chip systems: A critical review
2023年5月1日 · The advances in 3D skin models along with skin-on-a-chip (SOC) are reviewed. The collaboration of 3D bioprinting and SOC might hold the promise in creation of fully functional skin models. Download: Download high-res image (79KB)
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