Skin immune system - DermNet
The skin has an immune system that protects the body from infection, cancer, toxins, and attempts to prevent autoimmunity, in addition to being a physical barrier against the external environment. The skin immune system is sometimes called skin-associated lymphoid tissue (SALT), which includes peripheral lymphoid … 展开
The immune system of the skin has elements of both the innate (nonspecific) and adaptive (specific) immune systems. Immune cells inhabit the epidermis and dermis. The key immune cells in the epidermis are: 1. Epidermal dendritic cells (Langerhans cells) 2. … 展开
The complement system is an enzymatic cascade of over 20 different proteins normally found in the blood. When an infection is present, the system is sequentially activated leading to events that help destroy the invading organism. The complementsystem … 展开
The adaptive immune response is specific to a pathogen and takes a longer time to elicit. Adaptive immunity requires the production of specific T lymphocytes to identify an antigen with … 展开
Skin immunity - Wikipedia
Some humoral and cellular components of the skin pass through the vessel lymph to get to the circulation. This circulation net has a big importance, it's the way of direct communication between the specific site of the skin and the lymph cells found inside the lymph node and the systematic tissues. The epidermis antigens are connected with some cells of the skin. Among them there are the APC, antigen presenting cells (Langerhans, dentritic and cutaneous). They capture the antig…
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Immunology and Skin in Health and Disease - PMC
In this article, we will describe how all of the cell populations within the skin contribute to immune responses, and the general principles and tools required for effective immunity. We will use …
Skin immunity: dissecting the complex biology of our body’s outer ...
2022年3月31日 · Here we provide an overview of skin as an immune organ, with reference to the broader context of mucosal immunology.
The immunological anatomy of the skin | Nature …
2018年11月14日 · Because many physical, chemical and microbial insults affect the skin, various types of immune cells reside in or are recruited into the skin to maintain skin homeostasis upon inflammatory...
Skin immunity: dissecting the complex biology of our body's outer ...
2022年4月1日 · Our skin contributes critically to health via its role as a barrier tissue, carefully regulating passage of key substrates while also providing defense against exogenous threats.
Skin Immunity - PMC
Immune system within the skin is located in both major structural compartments: epidermis and dermis and consist of several important types of immunocompetent cells.
The Dynamics of the Skin's Immune System - PubMed
2019年4月12日 · Deregulation of immune responses often leads to impaired healing and poor tissue restoration and function. In this review, we will discuss the defensive components of the …
Skin barrier immunology from early life to adulthood
2023年4月1日 · The physical, chemical, microbial, and immune barrier components of the skin form an interactive system, which contributes to cutaneous host defense and skin homeostasis …
Mechanisms regulating skin immunity and inflammation - Nature
2014年4月11日 · In this Review, we discuss recent findings that highlight the complex regulatory networks that control skin immunity, and we provide new paradigms for the mechanisms that …
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