Induced pluripotent stem cells (iPSCs): molecular mechanisms of ...
2024年4月26日 · The induced pluripotent stem cell (iPSC) technology has transformed in vitro research and holds great promise to advance regenerative medicine. iPSCs have the capacity for an almost unlimited...
Defining Human Pluripotency: Cell Stem Cell - Cell Press
2019年7月3日 · Human pluripotent stem cells harbor the capacity to differentiate into cells from the three embryonic germ layers, and this ability grants them a central role in modeling human disorders and in the field of regenerative medicine.
Hallmarks of pluripotency | Nature
2015年9月24日 · Pluripotent stem cells produce all cells of an organism, while multipotent or unipotent stem cells regenerate only specific lineages or tissues. Defining stem-cell potency relies upon...
Concise Review: Human Pluripotent Stem Cells to Produce Cell…
2017年12月13日 · Human pluripotent stem cells (PSCs) provide a promising resource to produce immune cells for adoptive cellular immunotherapy to better treat and potentially cure otherwise lethal cancers. Cytotoxic T cells and natural killer (NK) …
Hallmarks of pluripotency - PubMed
2015年9月24日 · Pluripotent stem cells produce all cells of an organism, while multipotent or unipotent stem cells regenerate only specific lineages or tissues. Defining stem-cell potency relies upon functional assays and diagnostic transcriptional, epigenetic and metabolic states.
Introduction to stem cells - ScienceDirect
2023年1月1日 · Human pluripotent stem cells (hPSCs) mainly include embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs). Embryonic stem cells are derived from the inner cell mass of the embryo. Induced pluripotent stem cells are …
What Are Stem Cells? – Biomedical Beat Blog – National Institute …
2024年11月27日 · Scientists can create a third type of stem cells, called induced pluripotent stem cells (iPSCs), in the laboratory.To do this, the scientists change differentiated adult cells, like human skin cells, back into a pluripotent state through exposure to specific cell culture conditions. These newly reprogrammed cells then act like embryonic stem cells and are highly useful in …
Pluripotent and Multipotent Stem Cells and Current Therapeutic ...
2021年4月21日 · Induced pluripotent stem (iPS) cells are derived from adult somatic cells, which are genetically reprogrammed by forced gene expression to an embryonic stem and are essential for preserving the defining properties of ES cells. 18 Reprogrammed induced pluripotent cell enables the development of an unlimited source of cells. 19, 20 IPS cells are i...
Human pluripotent stem cells: derivation and applications
2020年11月5日 · This poster highlights the derivation and differentiation of human pluripotent stem cells and outlines key applications of these cells, such as cell-based therapies, disease modelling, drug...
Generation of self-organized neuromusculoskeletal tri ... - Cell Press
3 天之前 · H9 hESCs (human embryonic stem cells), H9-iSHH hESCs, H1 hESCs, and RC01001A hiPSCs (human induced pluripotent stem cells) were maintained in a feeder-free culture condition. hiPSC line RC01001A was derived from the peripheral blood mononuclear cell of a 36-year-old male donor through Sendai virus vector-mediated reprogramming and was a ...