Phage Therapy: How It Works, Pros and Cons, Availability, and More
2019年1月14日 · Phage therapy is a potential treatment for bacterial infections. As an alternative to antibiotics, it has some promise, but more research is needed.
The promise of phages | Nature Biotechnology
2023年5月9日 · Phages are small viruses that can target and eliminate specific bacterial strains without compromising other microbial species within our bodies. The field has been slow to develop commercially,...
Bacteriophage Technology and Modern Medicine - PMC
Nowadays, phage-based technology has been developed for many purposes, including those beyond the framework of antibacterial treatment, such as to suppress viruses by phages, gene therapy, vaccine development, etc. Here, we highlighted the current progress in phage engineering technology and its application in modern medicine.
Current and future directions in bacteriophage research for …
2024年10月17日 · Phages are gaining attention for their ability to target drug-resistant bacteria, disrupt biofilms, and reach intracellular pathogens, offering promising alternatives to traditional antibiotics....
Phage therapy: From biological mechanisms to future directions
Increasing antimicrobial resistance rates have revitalized bacteriophage (phage) research, the natural predators of bacteria discovered over 100 years ago. In order to use phages therapeutically, they should (1) preferably be lytic, (2) kill the bacterial host efficiently, and (3) be fully characterized to exclude side effects.
A Comprehensive Review on Phage Therapy and Phage-Based …
2024年9月11日 · Phage-display technology leverages bacteriophages to present peptide or protein libraries on their surfaces, enabling the rapid identification of high-affinity ligands for therapeutic purposes. This section highlights its role in drug discovery, including target identification, lead optimization, and antibody and peptide drug development.
High throughput platform technology for rapid target ... - Nature
2024年7月11日 · We demonstrate high throughput screening by identifying target phages for select multidrug-resistant clinical isolates of Pseudomonas aeruginosa, Salmonella enterica, Escherichia coli, and ...
Phage therapy: From biological mechanisms to future directions
2023年1月5日 · Increasing antimicrobial resistance rates have revitalized bacteriophage (phage) research, the natural predators of bacteria discovered over 100 years ago. In order to use phages therapeutically, they should (1) preferably be lytic, (2) kill the bacterial host efficiently, and (3) be fully characterized to exclude side effects.
Genetic Engineering and Biosynthesis Technology: Keys to …
2023年8月14日 · Phages possess the ability to selectively eliminate pathogenic bacteria by recognizing bacterial surface receptors. Since their discovery, phages have been recognized for their potent bactericidal properties, making them a promising alternative to antibiotics in the context of rising antibiotic resistance.
Harnessing Synthetic Biology To Transform Phage Therapy | Technology …
4 天之前 · Reacting to the 2023-2024 UK House of Commons Science, Innovation and Technology Committee report on the antimicrobial potential of bacteriophages, Dr. Ken Bruce, senior lecturer at King’s College London, said: “The renewed interest in the use of phage therapy represents a positive step in terms of dealing with clinical infection. Phage ...