Perinucleolar compartment - Wikipedia
The perinucleolar compartment follows the mitotic pathway to form new daughter cells that are similar in size and shape to the mother cells. However, they can vary in size between different cancer cell lines.
The Perinucleolar Compartment - PMC
The perinucleolar compartment (PNC) is a subnuclear body characterized by its location to the periphery of the nucleolus. The PNC is a dynamic structure and is highly enriched in RNA-binding proteins and pol III RNA.
The perinucleolar compartment: structure, function, and utility in …
The perinucleolar compartment (PNC) is a nuclear body that forms under pathological conditions, specifically in cancer cells. Here, we summarize the current understanding of the PNC composition, and possible functions, along with its utility …
The Perinucleolar Compartment: RNA Metabolism and Cancer
The perinucleolar compartment (PNC) is a nuclear substructure associated with, but structurally distinct from, the nucleolus. The PNC contains several RNA processing proteins and several RNA pol III transcripts, which form novel complexes.
The Perinucleolar Compartment and Transcription - PMC
1998年10月10日 · The perinucleolar compartment (PNC) is a unique nuclear structure localized at the periphery of the nucleolus. Several small RNAs transcribed by RNA polymerase III and two hnRNP proteins have been localized in the PNC (Ghetti, A., S. Piñol-Roma, W.M. Michael, C. Morandi, and G. Dreyfuss. 1992.
Full article: The perinucleolar compartment: structure, function, …
2024年1月27日 · The perinucleolar compartment (PNC) is a nuclear body that forms under pathological conditions, specifically in cancer cells. Here, we summarize the current understanding of the PNC composition, and possible functions, along with its utility in the development of anti-cancer therapies.
The Perinucleolar Compartment - PMC - National Center for …
2009年5月5日 · The functional relevance of these NBs is beginning to be revealed. The perinucleolar compartment (PNC), a nuclear body located at the nucleolar periphery, is in comparison much less explored.
The perinucleolar compartment (PNC): detection by ... - PubMed
The perinucleolar compartment (PNC) is a dynamic, irregularly shaped, and electron-dense nuclear structure that is physically associated with the nucleolus (1). It is found predominantly in transformed cells and various cancer tissues, and rarely in normal cells (1).
The perinucleolar compartment - PubMed
The perinucleolar compartment (PNC) is a subnuclear body characterized by its location to the periphery of the nucleolus. The PNC is a dynamic structure and is highly enriched in RNA-binding proteins and pol III RNA.
The Perinucleolar Compartment: A Promising Target to Prevent …
2023年3月9日 · The perinucleolar compartment (PNC) is a dynamic nuclear body found in the periphery of the nucleolus of malignant solid tumor cells. PNC contains a mixture of RNA polymerases and RNA-binding proteins.