Pathophysiology of Hypertension | Circulation Research
2021年4月1日 · Primary (or essential) hypertension represents between 85% and 95% of human cases and has an unidentified cause. In contrast, secondary hypertension is caused by identifiable underlying conditions, including renal artery stenosis, pheochromocytoma, adrenal adenoma, or single-gene mutations.
The pathophysiology of hypertension - PMC - PubMed Central …
Patients with hypertension demonstrate abnormalities of vessel wall (endothelial dysfunction or damage), the blood constituents (abnormal levels of haemostatic factors, platelet activation, and fibrinolysis), and blood flow (rheology, viscosity, and flow reserve), suggesting that hypertension confers a prothrombotic or hypercoagulable state.
Essential Hypertension - StatPearls - NCBI Bookshelf
2023年7月20日 · Summarize the pathophysiology of essential hypertension and its pathological sequelae on organ systems throughout the body. Review the various treatment options for treating essential hypertension, both pharmacological as well as lifestyle modification strategies.
Pathophysiology of hypertension - Wikipedia
The pathophysiology of hypertension is an area which attempts to explain mechanistically the causes of hypertension, which is a chronic disease characterized by elevation of blood pressure. Hypertension can be classified by cause as either essential (also known as primary or idiopathic) or secondary. About 90–95% of hypertension is essential ...
Hypertension: pathophysiology and treatment - Oxford Academic
2004年6月1日 · Pathophysiology. Hypertension is a chronic elevation of blood pressure that, in the long-term, causes end-organ damage and results in increased morbidity and mortality. Blood pressure is the product of cardiac output and systemic vascular resistance.
CHAPTER 24: PATHOPHYSIOLOGY OF HYPERTENSION
The pathophysiology of hypertension involves the impairment of renal pressure natriuresis, the feedback system in which high blood pressure induces an increase in sodium and water excretion by the kidney that leads to a reduction of the blood pressure.
Cardiac and vascular pathophysiology in hypertension - PMC
Hypertension causes cardiac and vascular remodelling and hypertrophy. This helps to normalise left ventricular and arterial wall stress and may compensate for a reduction in myocardial fibre function to preserve cardiac output
Pathophysiology of Hypertension: Pathogenesis of Essential Hypertension …
2024年9月6日 · Factors that play an important role in the pathogenesis of hypertension include the aging process, genetics, activation of neurohormonal systems such as the sympathetic nervous system and...
Hypertension: physiology and pathophysiology - PubMed
Despite major advances in understanding the pathophysiology of hypertension and availability of effective and safe antihypertensive drugs, suboptimal blood pressure (BP) control is still the most important risk factor for cardiovascular mortality and is …
Pathophysiology of Hypertension - ScienceDirect
2024年1月1日 · In this chapter, we briefly review short-term and long-term BP control systems and how they interact to maintain tissue blood flow, salt and water balance, and overall homeostasis.