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  1. The FDA has approved secukinumab (Cosentyx) to treat moderate to severe hidradenitis suppurativa (HS) in adults. 1 The treatment is the second biologic approved to treat HS, a chronic, systemic, an...
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    The FDA has approved secukinumab (Cosentyx) to treat moderate to severe hidradenitis suppurativa (HS) in adults. 1 The treatment is the second biologic approved to treat HS, a chronic, systemic, an...
    www.ajmc.com/view/secukinumab-gains-fda-appro…

    Two authors (A.M.Č. and Z.B.M.) collected sources of information, read the reference abstracts, and included a total of 196 articles and published results of registered randomized controlled trials primarily focusing on the molecular pathophysiology of hidradenitis suppurativa, conservative therapy of hidradenitis suppurativa, as well as ...

    pmc.ncbi.nlm.nih.gov/articles/PMC8998913/

    There are currently 2 Food and Drug Administration-approved treatments for hidradenitis suppurativa, and both are biologic medication -- Adalimumab, a monoclonal antibody targeting tumor necrosis factor-alpha and Secukinumab, an interleukin-17A inhibitor.

    www.jaad.org/article/S0190-9622(24)02880-9/fulltext

    Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition that can be challenging to treat. Biologics and targeted small molecules have become an increasingly popular area of investigation for therapeutic development for moderate-to-severe HS, though only three biologics-adalimumab, sec …

    pubmed.ncbi.nlm.nih.gov/39060744/

    FDA approval based on robust Phase III data in which Cosentyx ® (secukinumab) showed rapid relief from symptoms of hidradenitis suppurativa (HS) as early as Week 2 1 ; As the only IL-17A inhibitor approved for HS, Cosentyx offers a meaningful new treatment option that demonstrated reductions in inflammatory nodules and abscesses, and flares 2

    www.novartis.com/us-en/news/media-releases/fda …
  2. Biologics in hidradenitis suppurativa: Progress and new directions ...

  3. Hidradenitis Suppurativa: New Targets and Emerging Treatments

  4. FDA approves Novartis Cosentyx® as the first new biologic …

  5. Hidradenitis Suppurativa: New Targets and Emerging …

    2024年7月26日 · Sayed C, Shi V, Hsiao J, Kokolakis G, Kirby B, Piguet V, et al. Bimekizumab efficacy by prior biologic treatment in patients with moderate to severe hidradenitis suppurativa: 48-week pooled data from the randomized, …

  6. New drug shows promise for Hidradenitis Suppurativa …

    2020年2月27日 · An early study for a new injectable treatment shows improvement in Hidradenitis Suppurativa (HS) activity and pain scores while demonstrating safety. Dr. Alice Gottlieb of Icahn School of Medicine at Mount …

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  8. Bimekizumab: A Promising Option for Moderate to …

    2024年7月9日 · These data support the use of bimekizumab as a promising new therapeutic option for patients with moderate-to-severe hidradenitis suppurativa. A total of 505 patients from BE HEARD I and 509 from BE HEARD II were …

  9. FDA approves Novartis Cosentyx® as the first new biologic …

  10. Secukinumab Gains FDA Approval to Treat Hidradenitis …

    2023年10月31日 · The FDA has approved secukinumab (Cosentyx) to treat moderate to severe hidradenitis suppurativa (HS) in adults. 1 The treatment is the second biologic approved to treat HS, a chronic, systemic ...

  11. Hidradenitis Suppurativa: Causes, Features, and Current Treatments