Nalorphine - Wikipedia
Nalorphine (INN Tooltip International Nonproprietary Name; also known as N-allylnormorphine; brand names Lethidrone and Nalline) is a mixed opioid agonist–antagonist with opioid antagonist and analgesic properties. [2] It was introduced in 1954 [3] and was used as an antidote to reverse opioid overdose and in a challenge test to determine ...
Nalorphine: Uses, Interactions, Mechanism of Action - DrugBank …
2016年2月26日 · Nalorphine is a mixed opioid agonist–antagonist. It acts at two opioid receptors—at the mu receptor it has antagonistic effects, and at the kappa receptors it exerts high-efficacy agonistic characteristics. It is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid dependence.
Nalorphine | C19H21NO3 | CID 5284595 - PubChem
Nalorphine is a mixed opioid agonist–antagonist. It acts at two opioid receptors—at the mu receptor it has antagonistic effects, and at the kappa receptors it exerts high-efficacy agonistic characteristics. It is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid dependence.
Nalorphine Definition & Meaning - Merriam-Webster
The meaning of NALORPHINE is a white crystalline compound C19H21NO3 that is derived from morphine and is used especially formerly as a respiratory stimulant to counteract poisoning by morphine and similar narcotic drugs.
Nalorphine - an overview | ScienceDirect Topics
Nalorphine is a synthetic opioid that produces kappa receptor agonist and mu receptor antagonist effects. Nalorphine is used most commonly to reverse the effects of the mu receptor agonists (see Table 26-1). R.S. Vardanyan, V.J. Hruby, in Synthesis of Essential Drugs, 2006.
Nalorphine: Uses, Dosage, Side Effects and More - MIMS
2024年11月13日 · Nalorphine: Antidotes & Detoxifying Agents. Our drug directory offers in-depth details on its uses, side effects, and more. Get the latest medication information and prescription drug insights today!
Nalorphine - an overview | ScienceDirect Topics
Nalorphine is an opioid antagonist with some properties similar to those of naloxone. In addition, it possesses some agonist properties. It reverses severe opioid-induced respiratory depression, but may exacerbate respiratory depression such as that induced by ethanol or other non-opioid central depressants.
Nalorphine hydrochloride - DrugBank Online
Nalorphine is a mixed opioid agonist–antagonist. It acts at two opioid receptors—at the mu receptor it has antagonistic effects, and at the kappa receptors it exerts high-efficacy agonistic characteristics. It is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid dependence. Cl.
NALORPHINE HYDROCHLORIDE - National Center for Advancing …
Nalorphine inhibits the cholinesterases of mouse brain, bovine erythrocytes and horse serum. It acts on mu-, k- and sigma-opioid receptors. Nalorfin by virtue of the agonistic effect has an analgesic effect but to a much lesser extent than morphine.
Nalorphine | definition of nalorphine by Medical dictionary
An early antagonist of most depressant and stimulatory effects of morphine and related narcotic analgesics; precipitates severe withdrawal symptoms in morphine addicts, and counteracts the respiratory depression produced by morphine and related compounds; when administered in the absence of narcotics, nalorphine has mildly analgesic and respirat...