Mucormycosis pathology - DermNet
Mucormycosis is a fungal infection caused by organisms of the Mucorales order. Rhizopus species are the most commonly involved. Lichthemia (formerly Absidia) and Mucor are other less common causes. Histology of mucormycosis. The fungal forms of mucormycosis are broad, non-septate hyphae (figure 1).
Mucormycosis: Pathogenesis and Pathology | Current Fungal
Jan 19, 2019 · Mucormycosis is an opportunistic fungal infection associated with high mortality. Understanding the pathogenesis and the resultant pathology in various organs enables to improve early diagnosis and treatment options.
Mucormycosis - StatPearls - NCBI Bookshelf
Jun 12, 2023 · Mucormycosis is characterized by tissue necrosis due to an invasion of blood vessels and subsequent thrombosis, which usually follows a rapid progression. The key to treatment is early and aggressive surgical debridement, along with high doses of intravenous antifungal therapy.[1]
Pathogenesis of Mucormycosis - PMC
Mucormycosis is a life-threatening infection that occurs in patients who are immunocompromised because of diabetic ketoacidosis, neutropenia, organ transplantation, and/or increased serum levels of available iron.
Laboratory diagnosis of mucormycosis: Present perspective
Mucormycosis, a life-threatening fungal infection, is caused by the members of order Mucorales. [1, 2] Mucormycosis presents as fulminant fungal infection in debilitated patients, primarily involving the rhinofaciocranium, lungs, gastrointestinal tract, skin and kidney.
Mucormycosis diagnosis revisited: Current and emerging …
To avoid fatal effects, mucormycosis must be detected as soon as possible. The diagnosis of mucormycosis is still difficult and although molecular approaches are advancing, histopathology, direct inspection and culture remain important tools.
Update on mucormycosis pathogenesis - PMC - National Center …
Mucormycosis is an increasingly common fungal infection with unacceptably high mortality. The recent sequencing genome projects of Mucorales and the development of gene manipulation have enabled significant advances in understanding the pathogenesis of mucormycosis.
Pathogenesis of Mucormycosis | Clinical Infectious Diseases
Feb 1, 2012 · Understanding the pathogenesis of mucormycosis and the host response to invading hyphae ultimately will provide targets for novel therapeutic interventions. In this supplement, we review the current knowledge about the virulence traits used by the most common etiologic agent of mucormycosis, Rhizopus oryzae. Because patients with elevated …
The mutual value of histopathology and ITS sequencing in the …
Jan 8, 2024 · At our academic centre, we identified 14 consecutive mucormycosis cases diagnosed by histopathology and subsequent ITS sequencing. Using histomorphological examination, fungal hyphae could be detected in all cases; however, morphological features were unreliable regarding specifying the taxa.
Mucormycosis (zygomycosis) - UpToDate
Mucormycosis is manifested by a variety of different syndromes in humans, particularly in immunocompromised patients and those with diabetes mellitus [1]. Devastating rhino-orbital …