Idarubicin - Wikipedia
Idarubicin / ˌaɪdəˈruːbɪsɪn / or 4-demethoxydaunorubicin is an anthracycline antileukemic drug. It inserts [1] itself into DNA and prevents DNA unwinding by interfering with the enzyme topoisomerase II. It is an analog of daunorubicin, but the absence of a methoxy group increases its fat solubility and cellular uptake. [2] .
Idarubicin Uses, Side Effects & Warnings - Drugs.com
Idarubicin is used in combination chemotherapy in adults to treat acute myeloid leukemia (AML), a type of blood cancer. Idarubicin may also be used for purposes not listed in this medication guide. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Idarubicin: Package Insert / Prescribing Info - Drugs.com
2024年1月4日 · Idarubicin package insert / prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions and pharmacology.
Idarubicin: Uses, Interactions, Mechanism of Action - DrugBank …
Idarubicin is an anthracycline antineoplastic agent used to treat acute myeloid leukemia (AML) in adults. An orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with …
Idarubicin: MedlinePlus Drug Information
Idarubicin is used treat acute myelogenous leukemia (AML; a type of cancer of the white blood cells) in combination with other medications. Idarubicin is in a class of medications called anthracyclines. It works by slowing or stopping the growth of cancer cells in your body.
Idarubicin (intravenous route) - Mayo Clinic
Idarubicin injection is used in combination with other medicines to treat acute myeloid leukemia (AML). Idarubicin belongs to the group of medicines known as antineoplastics (cancer medicines). It works by interfering with the growth of cancer cells, which are eventually destroyed.
IDArubicin: Dosage, Mechanism/Onset of Action, Half-Life
2020年2月9日 · Includes IDArubicin indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more.
Idarubicin: a brief overview on pharmacology and clinical use
Idarubicin exhibits features rendering this drug unique among anthracyclines. The higher lipophilicity leads to faster accumulation in the nuclei, superior DNA-binding capacity and consequently greater cytotoxicity compared to daunorubicin. A major advantage over this reference drug is its ability t …
Idarubicin Dosage Guide + Max Dose, Adjustments - Drugs.com
2024年6月26日 · Detailed Idarubicin dosage information for adults. Includes dosages for Acute Myeloid Leukemia and Acute Nonlymphocytic Leukemia; plus renal, liver and dialysis adjustments.
Idarubicin | C26H27NO9 | CID 42890 - PubChem
Idarubicin | C26H27NO9 | CID 42890 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.