Gene signature - Wikipedia
A gene signature or gene expression signature is a single or combined group of genes in a cell with a uniquely characteristic pattern of gene expression [1] that occurs as a result of an …
Mining gene expression profiles: expression signatures as …
Jul 3, 2007 · Gene expression data derived from DNA microarray studies have been shown to provide enormous potential for dissecting the complexity of cancer. Particularly useful has …
A Gene-Expression Signature as a Predictor of Survival in Breast …
Dec 19, 2002 · Using inkjet-synthesized oligonucleotide microarrays, we recently identified a gene-expression profile that is associated with prognosis in patients with breast cancer. 9 We …
An essential gene signature of breast cancer metastasis reveals ...
Jun 12, 2024 · These 264 genes represented an essential signature of breast cancer metastasis. In contrast, nonessential metastasis genes largely involved tumor biopsy site. The essential …
Gene-Expression Signatures in Breast Cancer | NEJM
Feb 19, 2009 · Gene-expression profiling with the use of DNA microarrays allows measurement of thousands of messenger RNA (mRNA) transcripts in a single experiment. Results of such …
DNA-based molecular classifiers for the profiling of gene expression ...
Apr 17, 2024 · Here, we introduce a universal DNA-based molecular classifier for profiling gene expression signatures and generating immediate diagnostic outcomes. The molecular …
Functional genomic imaging (FGI), a virtual tool for visualization of ...
1 day ago · Based on this, functional annotation, gene expression profiling, and cancer subtyping were performed to gain more detailed insights into gene expression patterns within different …
Single-cell transcriptomics link gene expression signatures to
Nov 15, 2024 · Results: In lactotroph PitNET, we detect a highly proliferative gene profile with significantly increased expression levels in aggressively growing tumors within bulk RNA-seq …
SigMat: a classification scheme for gene signature matching
Jun 27, 2018 · Matching a gene signature, i.e. expression profile of a sample or set of dysregulated genes in a sample, to a library of pre-determined signatures is a common step in …
Detecting signatures of selection on gene expression
May 12, 2022 · First, we outline the main approaches for describing gene expression evolution, examine their inherent biases and synthesize findings to provide new perspectives to the …