Charcot-Marie-Tooth Disease (CMT) - Muscular Dystrophy …
What is Charcot-Marie-Tooth disease (CMT)? Charcot-Marie-Tooth disease (CMT) is a spectrum of nerve disorders named after the three physicians who first described it in 1886 — Jean-Martin Charcot and Pierre Marie of France and Howard Henry Tooth of the United Kingdom.
Simply Stated: What is CMT? - Muscular Dystrophy Association
2017年9月14日 · What happens in CMT? Degeneration of motor nerves results in muscle weakness and atrophy in the arms, legs, hands or feet, and the degeneration of sensory nerves results in a reduced ability to feel heat, cold and pain.
Charcot-Marie-Tooth Disease (CMT) - Muscular Dystrophy …
MDA is the #1 health nonprofit advancing research, care and advocacy for people living with muscular dystrophy, ALS, and related neuromuscular diseases. Partly because there are different types of Charcot-Marie-Tooth disease (CMT), the exact …
Charcot-Marie-Tooth Disease (CMT) - Muscular Dystrophy …
What is severe, early-onset Charcot-Marie-Tooth (CMT)? Early-onset CMT is a subtype of CMT that is a particularly severe variant of the disease. Other terms used to describe this variant include CMT3, Dejerine-Sottas disease, and congenital hypomyelinating neuropathy.
Charcot-Marie-Tooth Disease (CMT) - Muscular Dystrophy …
What is Charcot-Marie-Tooth disease type X (X-linked, CMTX)? CMTX is a subtype of CMT, a genetic, neurological disorder that causes damage to the peripheral nerves — tracts of nerve cell fibers that connect the brain and spinal cord to muscles and sensory organs.
Charcot-Marie-Tooth Disease (CMT) - Muscular Dystrophy …
Because of these features, CMT is sometimes called hereditary motor and sensory neuropathy (HMSN). Some doctors also use the older name, peroneal muscular atrophy, which refers to atrophy of the peroneal muscle in the lower part of the leg. CMT can run in a family, even when there is no obvious family history.
Charcot-Marie-Tooth Disease (CMT) - Muscular Dystrophy …
The many types of CMT are distinguished by age of onset, inheritance pattern, severity, and whether they are linked to defects in axon or myelin. The major categories of CMT are types 1 through 7 and the X-linked category, CMTX.
Charcot-Marie-Tooth Disease (CMT) - Muscular Dystrophy …
What is Charcot-Marie-Tooth disease type 1 (CMT1)? CMT type 1 is the most common subtype of CMT, accounting for roughly two-thirds of all cases. CMT1 is inherited in an autosomal dominant pattern.
Charcot-Marie-Tooth Disease (CMT) - Muscular Dystrophy …
Other procedures sometimes used to diagnose CMT include electromyography (EMG), which measures the electrical signals in muscles, and less commonly, nerve biopsy, which involves the removal and examination of a small piece of nerve.
Charcot-Marie-Tooth Disease (CMT) - Muscular Dystrophy …
MDA is the #1 health nonprofit advancing research, care and advocacy for people living with muscular dystrophy, ALS, and related neuromuscular diseases. Management of CMT is currently supportive; however, such supportive therapy can dramatically improve a patient’s quality of life.