Buclizine: Uses, Interactions, Mechanism of Action - DrugBank …
2005年6月13日 · Buclizine is a piperazine-derivative antihistamine used as an antivertigo/antiemetic agent. Buclizine is used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus.
H1 Antihistamines: Current Status and Future Directions - PMC
Cetirizine, desloratadine, fexofenadine, levocetirizine, loratadine, and other second-generation H 1 antihistamines have significantly greater efficacy than placebo, as documented in well-designed, randomized, placebo-controlled trials (Table 4A).
第二代抗組織胺的比較 - 微笑藥師網
2014年12月10日 · Cetirizine 懷孕分級：B. 第一代Hyroxyzine代謝物，為 周邊H1-受體的一種強效具選擇性拮抗劑，此藥特別處在於其 能 抑制LTC4及D4的製造 ，同時抑制嗜伊紅細胞的趨化(eosinophil chemotaxis)，另外還能 抑制由VIP(Vasoactive Intenstinal Polypetide)和Substance P所引起之過敏反應 。
Buclizine is prescribed exclu-sively as an antiemetic in the treat-ment of migraine whereas cyproheptadine (Periactin), which has antihistamine, antiserotonin and calcium-channel blocking activity, is sometimes used as pro-phylaxis of refractory migraine.
H1 Antihistamines: Current Status and Future Directions
2008年1月1日 · Second-generation H 1 antihistamines such as cetirizine, desloratadine, fexofenadine, levocetirizine, and loratadine cross the blood-brain barrier to a significantly smaller extent than their predecessors. The clinical pharmacology, efficacy, and safety of these medications have been extensively studied.
Buclizine, cyclizine, and meclizine are used to treat and prevent motion sickness, with the antiemetic effect of meclizine thought to be mediated through the chemoreceptor trigger zone.
Cetirizine: Uses, Interactions, Mechanism of Action - DrugBank …
2014年9月22日 · The risk or severity of QTc prolongation can be increased when Cetirizine is combined with Buclizine. Budesonide Cetirizine may decrease the excretion rate of Budesonide which could result in a higher serum level.
西替利嗪 - 百度百科
西替利嗪（Cetirizine）是一种抗过敏药，它是第二代H1抗组胺药，为长效的具选择性的口服强效抗变态反应药。 用于季节性或常年性过敏性鼻炎、由过敏原引起的荨麻疹及皮肤瘙痒。
Cetirizine - Wikipedia
Cetirizine is a second-generation antihistamine used to treat allergic rhinitis (hay fever), dermatitis, and urticaria (hives). [5] It is taken by mouth. [6] Effects generally begin within thirty minutes and last for about a day. [6] The degree of benefit is similar to other antihistamines such as diphenhydramine, which is a first-generation antihistamine. [6]
盐酸布克力嗪(Buclizine Hydrochloride) - 药物靶点：H1 receptor_ …
The pharmacological suppression of TCTP using buclizine results in regeneration suppression. Following the combinatorial injection of 2 mM Thymidine and buclizine, the earthworm regeneration is completely blocked, which suggests a critical functional role …
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