Spontaneous reporting of adverse reactions to carbimazole and ...
Neutrophil dyscrasia is the commonest life-threatening ADR to thionamides. The excess of ADR reports for propylthiouracil compared to carbimazole could reflect genuine differences in toxicity between the compounds, the relative unfamiliarity of UK physicians with propylthiouracil, or the higher use of propylthiouracil in certain patient groups.
Spontaneous Adverse Drug Reaction (ADR) Reports In Malaysia Since year 2000, the National Pharmaceutical Control Bureau (NPCB) has received 161 spontaneous ADR reports (292 adverse events) related to carbimazole, and 39 reports (70 events) related to PTU[6].
Suspected Spontaneous Reports of Birth Defects in the UK …
2011年9月13日 · We aimed to establish whether suspected spontaneous reporting of adverse drug reactions in the UK via the Yellow Card Scheme supports a carbimazole embryopathy and the lack of association between propylthiouracil and congenital anomalies.
Carbimazole | Drugs | BNF | NICE
View carbimazole information, including dose, uses, side-effects, pregnancy, breast feeding, contra-indications and important safety information.
Product name : Carbimazole CBnumber : CB3731303 CAS : 22232-54-8 EINECS Number : 244-854-4 Synonyms : Carbimazole,CARBIMAZOLE CRS Relevant identified uses : For R&D use only. Not for medicinal, household or other use. Uses advised against : none Company : …
甲亢平 - 百度百科
甲亢平，又名卡比马唑，化学名为3-甲基-2-硫代咪唑啉-1-羧酸乙酯，是一种有机化合物，化学式为C7H10N2O2S，为白色或类白色结晶性粉末，主要用作抗甲状腺药，用于治疗甲状腺亢进，是他巴唑的前体，在体内转化为他巴唑，其作用和不良反应都与他巴唑相似，作用较缓慢，维持时间比他巴唑长。 哺乳期妇女禁用，甲状腺危象禁用。 5、作为131I放疗的辅助治疗。 [1] 1、哺乳期妇女禁用。 2、甲状腺危象禁用。 [1] 初始剂量每天30～40mg，最大剂量不超过每天60mg，分3～4 …
Carbimazole: Uses, Interactions, Mechanism of Action - DrugBank …
2005年6月13日 · Carbimazole is a carbethoxy derivative of methimazole. Its antithyroid action is due to its conversion to methimazole after absorption. It is used to treat hyperthyroidism and thyrotoxicosis. Mechanism of action
Suspected carbimazole induced acute cholestatic hepatitis: Case …
2021年1月1日 · Carbimazole (CBZ)-induced cholestatic hepatitis is a rare adverse drug reaction (ADR), with only seven cases of CBZ-induced cholestatic hepatitis reported to the Therapeutic Goods...
Propylthiouracil and carbimazole – use in pregnancy
Propylthiouracil is an antithyroid drug indicated for the total treatment of hyperthyroidism or in the treatment of the thyrotoxic patient prior to surgery or radioactive iodine therapy. It is marketed in Australia under the brand name PTU. Carbimazole is also an antithyroid drug indicated for hyperthyroidism.
Spontaneous reporting of adverse reactions to carbimazole and ...
2004年10月12日 · Neutrophil dyscrasia is the commonest life-threatening ADR to thionamides. The excess of ADR reports for propylthiouracil compared to carbimazole could reflect genuine differences in toxicity between the compounds, the relative unfamiliarity of UK physicians with propylthiouracil, or the higher use of propylthiouracil in certain patient groups.
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