Bacterial-Based Cancer Therapy (BBCT): Recent Advances, Current ...
Further, bacterial-based cancer therapy (BBCT) can be either used as a monotherapy or in combination with other anticancer therapies for better clinical outcomes. Here, we review recent advances, current challenges, and prospects of bacteria and bacterial products in the development of BBCTs.
Bacteria-cancer interactions: bacteria-based cancer therapy
2019年12月11日 · Compared with most other therapeutics, tumor-targeting bacteria have versatile capabilities for suppressing cancer. Bacteria preferentially accumulate and proliferate within tumors, where...
Bacterial-Based Cancer Therapy (BBCT): Recent Advances, Current …
2021年12月18日 · Among immunotherapies, the application of bacteria and bacterial-based products has promising potential to be used as treatments that combat cancer. Bacterial targeting of tumors has been developed as a unique therapeutic option that meets the ongoing challenges of cancer treatment.
Bacterial-Based Cancer Therapy (BBCT): Recent Advances, Current ...
2021年12月18日 · Further, bacterial-based cancer therapy (BBCT) can be either used as a monotherapy or in combination with other anticancer therapies for better clinical outcomes. Here, we review recent advances, current challenges, and prospects of bacteria and bacterial products in the development of BBCTs.
Advancements in synthetic biology-based bacterial cancer …
2023年10月1日 · Here we propose six modules for a successful synthetic biology-based bacterial cancer therapy, the modules include Payload, Release, Tumor-targeting, Biocontainment, Memory, and Genetic Circuit Stability Module.
Recent Advances in Bacteria-Based Cancer Treatment
2022年10月9日 · Owing to its unique mechanism of abundant pathogen-associated molecular patterns in antitumor immune responses, bacteria-based cancer immunotherapy has recently attracted wide attention. Compared to traditional cancer treatments such as surgery, chemotherapy, radiotherapy, and phototherapy, bacteria …
In comparison with other cancer therapeutics, bacterial-based therapies have capabilities for suppressing cancer. Bacteria are known to accumulate and proliferate in the tumor...
Recent Advances in Bacteria-Based Cancer Treatment - PMC
2022年10月3日 · In this review, we discussed the anticancer activity of bacterial cellular components, including bacterial specific virulence factors, bacterial toxins, bacterial enzymes, biosurfactant, the outer surface of Gram-positive bacteria, bacterial cell membranes, cell walls, biofilms formed by spontaneous aggregation, dormant spores formed by poor ...
Bacterial-based cancer therapy: An emerging toolbox for …
2021年10月1日 · In this review, we have summarized the applications and advantages of using bacteria for targeted tumor therapy (Scheme 1) in order to aid in the design of novel intelligent drug delivery systems. The current challenges and future prospects of tumor-targeting bacterial nanocarriers have also been discussed. 1. Introduction.
Bioengineering of bacteria for cancer immunotherapy
2023年6月15日 · Here, we provide a brief overview of the approaches and strategies underlying bacteria-based cancer immunotherapy (BCiT). We also describe and summarize research in the field of synthetic...