IABCS - Overview: B-Cell Phenotyping Profile for Immunodeficiency and ...
In addition to its utility in the diagnosis of the above-described primary immunodeficiencies, B-cell phenotyping may be used to assess reconstitution of B-cell subsets after hematopoietic stem cell or bone marrow transplant. This test is also used to monitor B-cell-depicting therapies, such as Rituxan (rituximab) and Zevalin (ibritumomab ...
Comprehensive phenotyping of human peripheral blood B …
Several published reports have reported the use of complex and effective staining for B cell phenotyping [1, 2, 3, 4, 5]. Here we show the method we use to distinguish the B‐cell subpopulations in the peripheral blood of patients with different diseases associated with …
B-CELL PHENOTYPE ANALYSIS: WHEN TO ORDER AND WHY
Key points include the impact of rituximab on B-cell levels, monitoring B cells following HSCT for GVHD, and the role of B-cell phenotyping in identifying abnormal B-cell phenotypes post-therapy. Overall, the document stresses the critical role of B-cell phenotyping in diagnosing and managing immune-related disorders.
Advances in Human B Cell Phenotypic Profiling - PMC - PubMed …
Coupling cytometry-based phenotypic B cell analysis with cell morphology, immunoglobulin gene analysis (V region usage and somatic hypermutation patterns), functional in vitro assays (including cytokine and antibody secretion), and profiling after B cell-targeted therapies can also further elucidate the mechanisms driving such diseases, paving ...
Comprehensive phenotyping of human peripheral blood B …
Different B cell subsets, reflecting the maturation stages of B cells, have noninterchangeable functions and roles in innate and adaptive immune responses. In this review, we provide an overview of the B cell subsets present in peripheral blood of healthy individuals.
B Cell Subset Analysis | ARUP Laboratories Test Directory
Support the diagnosis of common variable immune deficiency (CVID) and assist in predicting the clinical phenotype. Assess B cell reconstitution after bone marrow or hematopoietic stem cell transplantation. Not recommended for rituximab monitoring; refer …
Immunophenotyping of B Cells by Flow Cytometry - Bio-Rad
This guide to immunophenotyping of human B cells takes you through some of the common markers and gating strategies used to identify B cells by flow cytometry, with examples of data acquired on the ZE5™ Cell Analyzer.
B cell markers - Abcam
2024年4月24日 · Studying this particular cell group can reveal the inner workings of the immune system, illuminating the possible causes behind various immune disorders and cancers. B cell generation begins in the bone marrow where stem cells give rise to lymphoid cells.
Immune Assessment B Cell Subsets, Blood - Quest Diagnostics
T- and B-Cell Quantitation by Flow Cytometry B-Cell Phenotyping Screen for Immunodeficiency and Immune Competence; Methodology. Flow Cytometry (FC) Reference Range(s) See Laboratory Report. LOINC® Codes, Performing Laboratory
Comprehensive phenotyping of human peripheral blood B
Different B cell subsets, reflecting the maturation stages of B cells, have noninterchangeable functions and roles in innate and adaptive immune responses. In this review, we provide an overview of the B cell subsets present in peripheral blood of healthy individuals.