Vectors for the treatment of autoimmune disease | Gene Therapy …
2003年5月6日 · In this article, we outline recent developments in gene therapy vectors, discuss advantages and disadvantages of each, and highlight their recent applications in autoimmune models.
Autoimmune Disease vectors - Shutterstock
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Calculation of Similarity Between 26 Autoimmune Diseases …
2021年11月11日 · In this work, we first computed the genetic similarity between 26 ADs based on three measurements: network similarity (NetSim), functional similarity (FunSim), and semantic similarity (SemSim), and systematically identified three significant pairs of similar ADs: rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), myasthenia gravis...
Antigen-specific immunotherapies for autoimmune disease
4 天之前 · Current therapies for autoimmune diseases target inflammation but are immunosuppressive and do not directly address the underlying cause of disease, which is a failure of immune tolerance to self.
Evolving understanding of autoimmune mechanisms and new …
2024年10月4日 · Autoimmune disorders such as multiple sclerosis (MS), type 1 diabetes (T1D) and rheumatoid arthritis (RA) occur when autoreactive immune cells, especially T cells and B cells are overactivated...
Machine learning application in autoimmune diseases: State of …
2024年2月1日 · In this work, we examine the literature focusing on the use of machine learning in the field of the main systemic (systemic lupus erythematosus and rheumatoid arthritis) and organ-specific autoimmune diseases (type 1 diabetes mellitus, …
Frontiers in CAR-T cell therapy for autoimmune diseases
2024年9月1日 · In this review, we discuss the mechanisms by which CAR-T cells target autoimmune conditions, summarize current preclinical models, and highlight ongoing clinical trials, including CAR-T therapy design, clinical outcomes, and challenges.
2,300+ Autoimmune Disease Stock Illustrations, Royalty-Free Vector …
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Immune Responses to Viral Gene Therapy Vectors - Cell Press
Past and ongoing clinical trials have utilized several different viral vectors, including adenovirus (Ad), adeno-associated virus (AAV), lentivirus (LV), murine γ-retrovirus, and herpes simplex virus (HSV).