Apolipoprotein E - Wikipedia
Apolipoprotein E (Apo-E) is a protein involved in the metabolism of fats in the body of mammals. A subtype is implicated in Alzheimer's disease and cardiovascular diseases. [5] It is encoded in …
载脂蛋白E - 百度百科
载 脂蛋白 E (apolipoprotein E，ApoE)是一种 多态性 蛋白，参与脂蛋白的转化与代谢过程，其基因可以调节许多生物学功能，与许多眼科疾病发病有关，对ApoE及其 基因多态性 的研究是医学 …
Apolipoprotein E - A Multifunctional Protein with Implications in ...
Apolipoprotein E (apoE), a 34 kDa glycoprotein, mediates hepatic and extrahepatic uptake of plasma lipoproteins and cholesterol efflux from lipid-laden macrophages. In humans, three …
Apolipoprotein E: structure and function in lipid metabolism ...
Apolipoprotein (apo) E is a multifunctional protein with central roles in lipid metabolism, neurobiology, and neurodegenerative diseases. It has three major isoforms (apoE2, apoE3, …
Apolipoprotein E: from lipid transport to neurobiology - PMC
Apolipoprotein E (apoE) is a potent modulator of plasma lipoprotein and cholesterol levels whose mode of action is mediated by interaction with members of the low-density lipoprotein (LDL) …
Apolipoprotein E and Alzheimer disease: pathobiology and …
2019年7月31日 · The apolipoprotein E (APOE) gene has three major allelic variants, APOE*ε2, APOE*ε3 and APOE*ε4; APOE*ε4 is associated with an increased risk and lower age of onset …
APOE gene - MedlinePlus
The APOE gene provides instructions for making a protein called apolipoprotein E. This protein combines with fats (lipids) in the body to form molecules called lipoproteins. Lipoproteins are …
APOE apolipoprotein E [Homo sapiens (human)] - Gene - NCBI
5 天之前 · The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of …
Apolipoprotein E structure: insights into function: Trends in ...
Human apolipoprotein E (apoE) is a member of the family of soluble apolipoproteins. Through its interaction with members of the low-density lipoprotein receptor family, apoE has a key role in …
ApoE in Alzheimer’s disease: pathophysiology and therapeutic …
2022年11月8日 · Among the increasing number of genetic risk factors identified, the apolipoprotein E (APOE) gene remains the strongest and most prevalent, impacting more than …