Neuronal types in the mouse amygdala and their transcriptional …
2023年10月26日 · Here we present a detailed cell-type taxonomy of the adult mouse amygdala during fear learning and memory consolidation. We perform single-cell RNA sequencing on naïve and fear-conditioned...
Amygdala intercalated cells form an evolutionarily conserved …
2024年12月13日 · Kuerbitz, J. et al. Loss of intercalated cells (ITCs) in the mouse amygdala of Tshz1 mutants correlates with fear, depression, and social interaction phenotypes. J. Neurosci. 38 , 1160–1177 (2018).
The Mouse Amygdaloid Body - SpringerLink
2020年2月29日 · This chapter will make you familiar with the peculiarities of the mouse amygdaloid body or amygdala. The amygdala is the main brain structure for the processing of emotional behavior. The different subnuclei and their functional connectivity will be dealt with. The Klüver-Bucy syndrome will be presented as an example for amygdala dysfunction.
Connectivity characterization of the mouse basolateral ... - Nature
2021年5月17日 · We identify brain-wide targets of projection neurons in the three BLAa domains, as well as in the posterior BLA, ventral BLA, posterior basomedial, and lateral amygdalar nuclei. Inputs to each...
Whole-Brain Map of Long-Range Monosynaptic Inputs to Different Cell ...
Here, we used a retrograde trans-synaptic rabies virus to generate a whole-brain map of inputs to the main cell types in the mouse amygdala. We identified 37 individual regions that projected to neurons expressing vesicular glutamate transporter 2, 78 regions to parvalbumin-expressing neurons, 104 regions to neurons expressing protein kinase C ...
The interhemispheric amygdala-accumbens circuit encodes
We found that in mice, transection of the anterior commissure (AC), which connects the rostroventral forebrain, impaired avoidant behaviors. The basolateral amygdala (BLA) in the mouse projects to the contralateral nucleus accumbens (NAc) through the AC, independent of its ipsilateral projections.
Novel Perspectives on the Development of the Amygdala in …
2021年12月8日 · Recently, the concentric ring theory of the pallium and the radial histogenetic model of the pallial amygdala have cleared up several uncertainties that plagued previous models of amygdalar development. Here, we provide an extensive overview on the developmental origin of the nuclei of the amygdaloid complex.
Comparative basolateral amygdala connectomics reveals …
We found that BLA neurons are more likely to project to multiple distinct parts of FC in mice than in macaques. Further, while single BLA neuron projections to nucleus accumbens were similarly organized in mice and macaques, BLA-FC connections differed substantially.
Transcriptomics reveals amygdala neuron regulation by fasting …
2023年5月24日 · The classical view is that brain circuits controlling homeostatic feeding are mainly located in the hypothalamus, whereas hedonic feeding is controlled by the limbic and reward systems, including hippocampus, amygdala, prefrontal cortex (PFC), nucleus accumbens (NAc), and ventral tegmental area (VTA) (1, 2).
Neuronal types in the mouse amygdala and their transcriptional …
The amygdala is a brain region primarily associated with emotional response. The use of genetic markers and single-cell transcriptomics can provide insights into behavior-associated cell state changes. Here we present a detailed cell-type taxonomy of the adult mouse amygdala during fear learning and memory consolidation.
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