Who Is Who in Adenosine Transport - PMC - PubMed Central (PMC)
Extracellular adenosine concentrations are regulated by a panel of membrane transporters which, in most cases, mediate its uptake into cells. Adenosine transporters belong to two gene …
Adenosine transporters - ScienceDirect
1996年6月1日 · Success in cloning the remaining adenosine transporter genes will improve our understanding of the diversity of nucleoside transport processes, with a view to better targeting …
The adenosine transporter, ENT1, in cardiomyocytes is sensitive …
The adenosine transporter 1 (ENT1) transports nucleosides, such as adenosine, and cytotoxic nucleoside analog drugs. ENT1 is well established to play a role in adenosinergic signaling in …
Adenosine transporters - PubMed
In mammals, nucleoside transport is an important determinant of the pharmacokinetics, plasma and tissue concentration, disposition and in vivo biological activity of adenosine as well as …
Structures of human ENT1 in complex with adenosine reuptake …
2019年6月24日 · The human equilibrative nucleoside transporter 1 (hENT1), a member of the SLC29 family, plays crucial roles in adenosine signaling, cellular uptake of nucleoside for DNA …
Distribution and Functional Characterization of Equilibrative ...
2006年7月27日 · Adenosine plays multiple roles in the efficient functioning of the heart by regulating coronary blood flow, cardiac pacemaking, and contractility. Previous studies have …
Who Is Who in Adenosine Transport - PubMed
2018年6月14日 · Extracellular adenosine concentrations are regulated by a panel of membrane transporters which, in most cases, mediate its uptake into cells. Adenosine transporters belong …
Physiological Roles of Vascular Nucleoside Transporters
2007年3月1日 · Once generated into the extracellular space, adenosine can activate endothelial ARs or is taken up by passive (ENTs) or active nucleoside transporters (adenosine-sodium co …
Control of Adenosine Transport by Hypoxia | Circulation Research
2005年7月8日 · The adenosine transporter, mENT1, is a target for adenosine receptor signaling and protein kinase Cepsilon in hypoxic and pharmacological preconditioning in the mouse …
Chapter Fifteen - Adenosine Transporters and Receptors
2015年1月1日 · Adenosine transporters are divided into equilibrative and concentrative, and the major transporter subtype present in the retina is the ENT1. This transporter is responsible for …