Myosin ATPase - an overview | ScienceDirect Topics
The background, experimental methods, and dynamics of myosin and actomyosin ATPase activities are described. Myosins are the molecular motors best known for powering muscle contraction, but nonmuscle isoforms serve as intracellular cargo transporters, cytoskeletal anchors, and signaling molecules.
KINETIC AND EQUILIBRIUM ANALYSIS OF THE MYOSIN ATPase
The myosin superfamily consists of more than 35 classes (each consisting of multiple isoforms) that have diverse cellular activities. The reaction pathway of the actin-activated myosin ATPase appears to be conserved for all myosin isoforms, but the ...
Myosin ATPase - an overview | ScienceDirect Topics
Myosin ATPase is an enzyme that hydrolyzes ATP along a specific reaction pathway, playing a crucial role in muscle contraction and cellular motility. AI generated definition based on: Comprehensive Biophysics, 2012
Myosin: Formation and maintenance of thick filaments - PMC
Thus, S1 determines the biochemical and physiological functions of myosin, such as ATPase activity and actin‐filament velocity (Resnicow, Deacon, Warrick, Spudich, & Leinwand, 2010). The rod domain is proteolytically cleaved into subfragment‐2 (S2) and light meromyosin (LMM).
Actin, Myosin, and Cell Movement - The Cell - NCBI Bookshelf
Myosin is the prototype of a molecular motor—a protein that converts chemical energy in the form of ATP to mechanical energy, thus generating force and movement. The most striking variety of such movement is muscle contraction, which has provided the model for understanding actin-myosin interactions and the motor activity of myosin molecules.
Myosin isoforms and the mechanochemical cross-bridge cycle
One feature of the myosin ATPase cycle is that it involves an association/dissociation with actin for each ATP hydrolysed. The cycle has been described in detail for a large number of myosins from different classes.
Review: The ATPase mechanism of myosin and actomyosin
In this short review I will outline current thinking on the mechanism of ATP hydrolysis and how the energy of ATP hydrolysis is coupled to a series of protein conformational changes that allow a myosin, with the cytoskeleton track actin, to operate as a molecular motor of distinct types; fast movers, processive motors or strain sensors. © 2016 ...
The Structural Basis of the Myosin ATPase Activity
Myosin is an ATPase that converts chemical energy into directed movement and can be viewed as a molecular motor. This protein comes in many shapes and sizes. Over 11 classes of myosin have been identified, and it is anticipated that more will be found as the search continues (2).
The role of the myosin ATPase activity in adaptive thermogenesis …
2011年3月23日 · The control of temperature in homotherms is so important that multiple mechanisms have been evolved to achieve it. I propose below that the myosin ATPase activity constitutes one of the “furnaces” that produces adaptive thermogenesis in resting skeletal muscle.
Toward understanding actin activation of myosin ATPase: The …
2006年4月18日 · Although still unconnected, there are now also ideas about how myosin catalyzes ATPase in the pocket . We see the present findings and surmise an as yet incomplete filling of a gap: how myosin anchors to actin and how actin then prepares myosin for its catalytic and thrusting function.
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