【干货】Cre-loxP重组酶系统介绍 - 知乎 - 知乎专栏
Cre-loxP重组酶系统的作用方式 . Cre重组酶识别loxP位点两端的反向重复序列并结合形成二聚体，然后此二聚体与另一个loxP位点上的二聚体结合形成一个四聚体。LoxP位点是有方向性的，四聚体连接的两个位点在方向上是平行的。
Cre-Lox recombination - Wikipedia
Cre-Lox recombination is a site-specific recombinase technology, used to carry out deletions, insertions, translocations and inversions at specific sites in the DNA of cells. It allows the DNA modification to be targeted to a specific cell type or be triggered by a specific external stimulus.
Cre重组酶 - 百度百科
Cre(Cyclization Recombination Enzyme,即环化 重组酶 ）是来源于 噬菌体 P1的一种 酶蛋白 ，分子量约38kDa。 它可以识别催化两个LoxP位点之间发生 同源重组 ，从而造成DNA的缺失、易位等现象。
又见Cre！Cre/Loxp系统应用全攻略 | 知识点分享 - 知乎
Cre（Cyclization Recombination Enzyme）是一种重组酶，来源于P1噬菌体，其基因编码区序列全长1029bp，为38kDa大小的、由343个氨基酸组成的多肽单体蛋白。 Cre重组酶的C-末端结构域包含催化活性位点，能够催化DNA分子中特定位点之间的重组，同时，Cre还能识别特异的DNA ...
Cre-lox系统介绍及使用汇总 - 知乎 - 知乎专栏
环化重组酶（Cre, cyclization recombinase），是酪氨酸位点特异性重组酶之一，能催化两个DNA识别位点之间的位点特异性重组。Cre重组酶来源于P1噬菌体，由 343个氨基酸组成，能特异性地识别Lox位点。除Cre以外，此类重组酶还有Flp（flipase）和Dre（D6特异性重组酶）。
Cre recombinase - Wikipedia
The enzyme's ability to operate efficiently in a wide range of cellular environments (including mammals, plants, bacteria, and yeast) enables the Cre-Lox recombination system to be used in a vast number of organisms, making it a particularly useful tool in scientific research.
Cre-loxP-Mediated Recombination: General Principles and Experimental ...
2017年3月2日 — The cre-loxP-mediated recombination system (the "cre-loxP system") is an integral experimental tool for mammalian genetics and cell biology. Use of the system has greatly expanded our ability to precisely interrogate gene function in the mouse, providing both spatial and temporal control of gene exp …
Cre-Lox Recombination - an overview | ScienceDirect Topics
Cre-Lox recombination is a genetic technique that involves the use of the Cre recombinase enzyme to manipulate DNA sequences flanked by specific loxP sites, leading to deletions, inversions, or translocations in a controlled manner.
The Cre- loxP System: A Powerful Tool in the Genetic Toolbox
2023年12月4日 — Cre-loxP recombination allows scientists to excise, insert, or invert specific DNA segments with unprecedented accuracy. This works through two key components: a Cre recombinase and loxP sequence recognition sites.
The need for Cre-loci controls in conditional mouse experiments:
2 天之前 — The Cre/loxP system has revolutionized medical research by enabling site-specific recombination, thus laying the groundwork for its widespread application . This system allows for precise ...