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  1. Springer
    https://link.springer.com › protocol

    Immunoenzymatic Assays to Target Central and Peripheral …

  2. 其他用户还问了以下问题
    What is pepstatin A?
    Gianni Marone, in Mast Cells and Basophils, 2000 Pepstatin A is a natural pentapeptide that has been isolated from culture filtrates of various species of actinomycetes (99) and which plays an important role in several lung diseases, including hypersensitivity pneumonitis (100–102).

    Pepstatin - an overview | ScienceDirect Topics

    sciencedirect.com
    Is pepstatin A catalytic inhibitor?
    Pepstatin contains an unusual amino acid, 3-hydroxy-4-amino-6-methylheptanoic acid. The 3-OH group binds to the two catalytic aspartic acids to form a transition-state analog, which provides very tight binding. Because all aspartic proteases have the identical catalytic mechanism, pepstatin is an excellent inhibitor.

    Pepstatin - an overview | ScienceDirect Topics

    sciencedirect.com
    Is pepstatin a chemoattractant?
    This pentapeptide is a potent chemoattractant from human neutrophils, monocytes and eosinophils (104). Pepstatin A also induces the release of lysosomal enzymes and the generation of superoxide anion (O 2–) from human neutrophils (105).

    Pepstatin - an overview | ScienceDirect Topics

    sciencedirect.com
    Is pepstatin a renin inhibitor?
    Pepstatin is a strong inhibitor of aspartyl proteases such as pepsin, cathepsin D, and renin. This natural pentapeptide isolated from actinomycetes was for many years the classic renin inhibitor in vitro.24 Pepstatin is not specific for renin and is poorly soluble in water.

    Pepstatin - an overview | ScienceDirect Topics

    sciencedirect.com
    How much does pepstatin a cost?
    COA for example only. Actual tests may differ. $12.99 Ground shipping (In continental US only.) Pepstatin A is an inhibitor of aspartic acid protease. It is highly selective without inhibiting thiol proteases, neutral proteases or serine proteases.

    Pepstatin A | GoldBio

    goldbio.com
    Can pepstatin be used as a site titrant of cathepsin D?
    Pepstatin and dansyl-pepstatin can be exploited as an active site titrant of cathepsin D [37,38]. Affinity chromatography on immobilized pepstatin has been used for purification of cathepsin D and procathepsin D [6,39].

    Pepstatin - an overview | ScienceDirect Topics

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