In the case of an accumulation of unfolded or misfolded proteins in the ER, cellular signalling pathways are induced in order to start an adaptive cellular response. This adaptive cellular response ...

The Rosalind Franklin Institute, Harwell Science & Innovation Campus, Harwell OX11 0FA, U.K. Department of Chemistry, University of Technology Sydney, 15 Broadway, Ultimo, Sydney, NSW 2007, Australia ...

X box-binding protein-1 (Xbp1) was newly identified as a transcription ... Conclusions ER stress in hepatocytes induces PHLDA3 via IRE1–Xbp1s pathway, which facilitates liver injury by inhibiting Akt.

A sequence of stress signals among specialized clean-up cells in the brain could at last reveal why some immune responses can cause significant nerve degeneration that results in the loss of memory, ...

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The protein ... tumoricidal response is initiated at the membrane by mechanisms involving membrane perturbations and ion fluxes. Subsequent responses include death signaling pathways and direct ...

Intentionally eating more protein has become one of the most popular diet changes in the past couple of years. In 2023, searches for the phrase "high protein" were the highest they had been in five ...

The following is a summary of “Clinical response and corresponding blood transcriptome pathways before and after treatment of hereditary angioedema prodromes compared to active swelling attacks,” ...