As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

Activation of hepatic stellate cells is the central event in hepatic fibrosis. These perisinusoidal cells orchestrate an array of changes including degradation of the normal ECM of liver ...

The organoid's response to ... Dec. 5, 2024 — Scientists have developed a 'molecular GPS' to guide immune cells into the brain and kill tumors without harming healthy ... Researchers Design ...

For most neuroscientists, the roots of our discipline stem from Santiago Ramón y Cajal, the Spanish scientist who, during almost half a century of patient work, showed that the nervous system is ...

The first clue that they might play different roles in hearing came about 40 years ago as the result of a painstaking anatomical investigation which revealed that most of the nerve fibers that carry ...

Jan. 15, 2025 — While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows.

mednet.ucla.edu Objective Neurotensin (NT) mediates colonic inflammation through its receptor neurotensin receptor 1 (NTR1). NT stimulates miR-133α expression in colonic epithelial cells. We ...

Siham Sabri and published in the journal Clinical Cancer Research from the American Association of Cancer Research, this molecule called ZR2002, administered orally and capable of penetrating the ...

Neuroscience is a multidisciplinary science that is concerned with the study of the structure and function of the nervous system. It encompasses the evolution, development, cellular and molecular ...

Parasitic infections can invade practically any part of the body. Brain parasites, those that infect the central nervous system which includes the brain, are potentially the most damaging and the most ...

Additionally, GM influences the immune system by interacting with epithelial cells and stimulating immune responses ... GM of fish and will select for several groups of bacteria producing compounds ...