Dysregulated cell signaling underlies various diseases, emphasizing the importance of understanding these pathways for ...

PEG-MGF, or polyethylene glycol-modified mechanogrowth factor, is a peptide that has garnered attention in scientific ...

Cordycepin, derived from fungi, shows promise in cancer therapy by inhibiting growth factor signaling pathways critical for ...

The signaling pathway, which is mediated by the protein GP130, plays a central role in cell communication and influences the activity of the transcription factor ... tumor growth can be slowed ...

Diabetes drug development gets an advance in study that shows Inceptor binds excess insulin within the beta cell and directs it towards degradation.

Nerve growth factor (NGF) can activate RET by its tyrosine kinase receptor TrkA through an unknown intracellular pathway ... As different GFLs signal through the same RET receptor, it is of ...

Transforming growth factor beta (TGFβ ... The role of Smad2/3 in the TGFβ pathway, independent of Smad4, is understudied. Authors reveal distinct roles for Smad2/3 and Smad4 during mESC priming ...

This study presents a valuable finding on a potential signaling pathway responsible for the direct effects of nicotine on intestinal stem cell growth and tumorigenesis ... Cigarette smoking is a ...

vascular endothelial growth factor; VEGF‐R, VEGF‐receptor. Although evidence suggests that VEGF direct or indirect involvement with IAs, a clear mechanistic pathway remains elusive. VEGF pleiotropic ...

This failure is likely largely attributed to the complex and multifactorial nature of aneurysm pathophysiology. Recent research has increasingly implicated vascular endothelial growth factor (VEGF) in ...

Now, a new study led by an international research team from MedUni Vienna has identified a promising approach that could not only slow down tumor growth ... the GP130 signaling pathway, a process ...