T cell populations including CD4+ helper T cells, CD8+ cytotoxic T cells and Foxp3+ regulatory T cells play a critical role in controlling or promoting inflammatory disease’s progression. In recent ...

Synthetic suppressor T cells could improve treatment for organ transplants, type 1 diabetes, and other autoimmune conditions.

This study reveals distinct immune subpopulations associated with specific myeloma cell genotypes and highlights the central ...

Cytotoxic T cells are CD8-postive T cells that are specialized for the direct killing of cells that are infected (particularly with viruses), cancerous or damaged in other ways. They express the ...

Data from the ongoing Phase 2 of EO4010 demonstrate tumor target specific immune responses and objective tumor responses, including in liver ...

Hepatocellular carcinoma (HCC) is a significant global health issue, ranking as the sixth most prevalent malignancy and the ...

Tumor cells transform fibroblasts into cancer-associated fibroblasts, which have an important immunosuppressive activity on which growth, invasion, and metastasis depend. These activated fibroblasts ...

The TIME is a dynamic network composed of cancer cells, immune cells, and stromal components. During the early stages of tumorigenesis, the TIME attempts to eliminate abnormal cells through immune ...

CD4-cell counts and T-cell activation levels were determined in four groups of patients: 30 HIV-infected elite controllers, 47 HIV-uninfected persons, 187 treated HIV-infected persons with ...