Chronic lymphocytic leukemia (CLL) affects lymphocytes. Lymphocytes are a type of white blood cell (WBC). CLL specifically affects B lymphocytes, which are also called B cells. Normal B cells ...
Chronic lymphocytic leukemia (CLL) has a relatively high survival ... Bone marrow is a soft, spongy substance within bones that produces blood cells. CLL is the result of various genetic mutations ...
Chronic lymphocytic leukemia-- or CLL-- is a type of cancer ... that something happens to change the genetic code inside your cells that make white blood cells. Normally, these cells help your ...
Patients with relapsed or refractory CD19-positive B-cell acute lymphoblastic leukemia ... it from the very different disease of chronic lymphocytic leukemia, which has a potential time course ...
chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) reveal that a changed score of −11/+11 for symptom burden, −16/+16 for physical condition/fatigue and −16/+13 for ...
Among the efficacy evaluable patients, 42% achieved complete remission within 3 months. The Food and Drug Administration (FDA) has approved Aucatzyl ® (obecabtagene autoleucel; obe-cel) for the ...
Obe-cel is the first FDA-approved CAR T-cell therapy for B-ALL without a REMS requirement, based on the FELIX trial's positive outcomes. The FELIX trial reported a 63% complete remission rate ...
Chronic lymphocytic leukemia (CLL) may have a genetic basis ... It occurs when blood cells begin to grow atypically. CLL may run in families, but there is also no evidence that genetic testing ...
We conducted a phase 1b–2 multicenter study of obe-cel in adults (≥18 years of age) with relapsed or refractory B-cell acute lymphoblastic leukemia (ALL). The main cohort, cohort 2A ...