A team of researchers has found a quicker and more efficient way to create nucleoside analogs, a type of small molecule that ...

but the yield of nucleosides reported in most prebiotic syntheses is poor. We have therefore investigated certain aspects of prebiotic nucleoside synthesis.

Deoxynucleoside analogues such as 5-aza-2-deoxycytidine (depicted by Z) are converted into the triphosphate inside S-phase cells and are incorporated in place of cytosine into DNA. Ribonucleosides ...

Obeldesivir (GS-5245), a novel investigational small molecule oral antiviral, represents a new tool in the ongoing effort to prepare for future pandemics. Several researchers at the University of ...

Inosine is a nucleoside that occurs naturally in transfer RNAs (tRNAs) and is essential for proper RNA translation. It is commonly found at the wobble position of anticodons, allowing for greater ...

The second group of drugs used to treat CHB is nucleoside/nucleotide analogues. Approved agents in this group are lamivudine (LVD), adefovir (ADV), entecavir and telbivudine (LdT). Clevudine has ...