Abstract Biliary atresia, a progressive sclerosis of the extrahepatic biliary tree that occurs only within the first 3 months of life, is one of the most common causes of neonatal cholestasis and ...

The underlying stimulus for the immune-mediated bile duct injury in biliary atresia may involve an insult (e.g., viral infection) to the bile duct epithelium that leads to upregulation of ICAM and ...

Lithocholic acid (LCA) is a hepatotoxic compound. Fetal LCA might play a role in the pathogenesis of neonatal cholestasis/EHBA. Recent results show that fetal liver has capacity for hydroxylations ...

Focal obliteration of bile ducts, secondary to cholangitis, was frequent, and may have been the cause of extrahepatic biliary atresia in two cases. The nature of the association between this ...