lung cancer research has classically focused on molecular drivers of disease. One such pathway, the hypoxic response pathway, is activated by reduced local oxygen concentrations at the tumor site.
When they compared the genes in the hypoxia-response signature of normal cells to that of different cancer cells ... genes that have impacts on both development and disease.
Deep in a tumor, full of rapidly dividing cells, cancer cells are faced with a lack of oxygen, a condition called hypoxia. Cancer cells that survive these tough environments end up seeking what ...
Deep in a tumor, full of rapidly dividing cells, cancer cells are faced with a lack of oxygen, a condition called hypoxia. Cancer cells that survive these tough environments end up seeking what ...
The liver is one of the organs in which hypoxia helps to regulate gene expression under normal physiological conditions, as well as diseases such as cirrhosis and cancer. Hypoxia enhances ...