SignalChem Biotech provides diverse recombinant Tau proteins for research, helping advance tau-targeted therapies that may ...

Tau is a protein that builds up and moves between nerve cells in the brains of people living with Alzheimer’s disease, causing damage. Professor Mudher is using clever genetic manipulation in fruit ...

Trimming Alzheimer's-linked proteins This new technique for targeting tau tangles utilizes a 2010 discovery from Dr. Leo ...

They consist of aggregates of abnormally phosphorylated tau proteins that are altered in conformation. Conformational changes in tau proteins are thought to be the earliest neurobiological changes ...

Tau is a microtubule-associated protein encoded by the MAPT gene located on chromosome 17q21. It promotes microtubule assembly and stability and may play a role in establishing and maintaining ...

Previous studies showed that tau is chemically modified in disease, predominantly by the addition of extra phosphate to the Tyrosine groups in the protein, and that these changes play a crucial ...

Increased levels of tau and the ... β and tau proteins); Neuropeptides may contribute to the enhancement of neuronal survival and functional recovery after TBI by inducing Akt activation and ...

The protein tau is essential to the function of cells in ... Tau modulation through AAV9 therapy augments Akt/Erk survival ...

A drug commonly used to treat glaucoma has been shown in zebrafish and mice to protect against the build-up in the brain of the protein tau, which causes various forms of dementia and is ...

A drug commonly used to treat glaucoma has been shown in zebrafish and mice to protect against the build-up in the brain of the protein tau, which causes various forms of dementia and is ...

Rather than knocking down or overexpressing TMEM106b as other mouse studies have done, Rothstein and colleagues wanted to investigate how the endogenous protein responded in the setting of TDP-43 or ...