Prior to the sequencing of the human genome and the advent of recombinant biology in the early 2000s, drug discovery was predominantly undertaken through phenotypic or pharmacological studies. Using ...

After working for years to understand how to apply an artificial intelligence (AI) approach to biotechnology, Insilico Medicine recently announced the discovery of a novel drug target and novel ...

The traditional drug discovery process of identifying the causal mechanism of a disease, a single molecular target, and a drug against the target is slow, expensive, and fraught with the fallout ...

resulting in compounds that more efficiently fill three-dimensional molecular space and better modulate the functions of specific target proteins. Chief among these methods are DNA-encoded chemistry ...

Researchers are empowering drug ... as a target for this research. Using Chemistry42 to generate compounds based on the predicted CDK20 structure from AlphaFold, more than 8918 molecules were ...

Functional genomics screening that leverages CRISPR/Cas9-based knockout plays a crucial role in drug target discovery, helping researchers connect systematic genetic perturbation with cellular ...

A new weight loss drug target may help reduce appetite and burn calories without causing sickness, research suggests. The ...

University of Copenhagen - The Faculty of Health and Medical Sciences Scientists at the University of Copenhagen have discovered a new weight loss drug target that reduces appetite, increases ...