Glycogen synthase kinase 3 (GSK3 ... and contributes to the stimulation of glycogen and protein synthesis. Figure 4: The molecular mechanism by which phosphorylation inhibits GSK3.

The molecular basis of phospho-tyrosyl-regulation of Src-family and Syk-family protein tyrosine kinases in signaling ... This insight from simulation suggests SEN as a mechanism for limiting the ...

WNKs sense osmotic pressure by binding specific water molecules to the inactive dimeric configuration of WNK1 and WNK3, integrating signals with chloride inhibition as demonstrated by mutagenesis and ...

A research group has discovered that in mammals, a protein kinase A (PKA) promotes wakefulness, while protein phosphatase 1 (PP1) and calcineurin promote sleep. This study revealed that the balance ...