In 1961 the structure of one protein, myoglobin, was known at 6 Å resolution and its 2 Å structure would soon be published. The structural determinations of hemoglobin and hen lysozyme were well ...

Protein structure and dynamics are intimately linked with biological activity. Understanding the physical basis for this activity requires knowledge of the equilibrium and kinetic properties of ...

If a protein folds incorrectly, it may not work properly and could lead to diseases such as Alzheimer's, cystic fibrosis or ...

In some cases, however, brains outlast all other soft tissues and remain intact for hundreds or thousands of years.

Based on this one-dimensional amino acid sequence, proteins fold into complex three-dimensional shapes that enable them to carry out their biological functions. A protein’s shape relates closely ...

Predicting how a protein folds into a unique three-dimensional shape has puzzled scientists for half a century. London-based AI lab, DeepMind, has largely cracked the problem, said the organisers ...

The Cancer Research UK-funded study looked at molecules in our cells that make sure proteins are folded properly, known as chaperones. The researchers examined the chaperone HSP90, responsible for ...

Protein folding has been an ongoing problem for researchers since 1972. Christian Anfinsen speculated in his Nobel Prize acceptance speech in that year that the three-dimensional structure of a ...

In a finding that offers fresh insights into the early evolution of life on Earth, two RIKEN biologists have conducted lab ...