These data suggest that the HPG axis is activated in premature female infants prior to their would be term delivery. The index case differed in that elevated E2 levels persisted and ovarian cysts ...

Adrenal steroidogenesis is under the control of the hypothalamic–pituitary–adrenal (HPA) axis. Furthermore, metabolic factors including insulin and obesity-related signals may play a role in ...

Obesity is often associated with PCOS, and its presence may be responsible for alterations of the hypothalamic–pituitary–adrenal axis. There are sufficient arguments to suggest that insulin ...