The American College of Medical Genetics and Genomics has just published its highly anticipated Evidence-Based Clinical ...

Sapropterin dihydrochloride 100mg, 500mg; per pkt; pwd for oral soln. Kuvan is a synthetic form of BH4, the cofactor for the enzyme phenylalanine hydroxylase (PAH). PAH hydroxylates Phe through an ...

an enzyme responsible for the hydroxylation of the amino acid phenylalanine (Phe) to tyrosine (Tyr), which is an important intermediate in the production of neurotransmitters. If PKU goes ...

PKU is a rare genetic disease that manifests at birth and is marked by an inability to break down phenylalanine (phe), an amino acid that is commonly found in many foods. Left untreated ...