Ondansetron (as HCl dihydrate) 2mg/mL; IV or IM inj. Ondansetron is a selective 5-HT3 receptor antagonist. Serotonin receptors of the 5-HT3 type are present both peripherally on vagal nerve ...

The most frequent side effects were mild headache (10%) and constipation (5%). The results of these three large trials established palonosetron as an active and well-tolerated new 5-HT3 antagonist.

5-HT3 antagonists are effective for the prevention of chemotherapy-related nausea and for the prevention and treatment of nausea caused by general anesthesia. Zofran is also considered one of the ...