What is TP53 and what role does it play in cancer? Medically reviewed by Marla Anderson, MD. The TP53 gene is a gene that is ...

How is a normal cell transformed into a cancerous cell? The proteins involved in cell division events no longer appropriately drive progression from one cell cycle stage to the next. Cells that ...

Tumor suppressor genes act as “brakes” to stop cells before they can travel down the road to cancer. A loss of function mutation in these genes can be disastrous. Like all genes, tumor ...

When gut bacteria breaks down plant fiber, they produce two compounds that act on genes to help prevent the growth of cancers ...

A little-known mouse protein disrupts cancer-causing chemical changes to genes associated with human colorectal cancer cells ...

Identification of genes inactivated by promoter CpG methylation is a powerful approach to discover novel tumor suppressor candidates. PCDH10suppresses gastric cancer cell growth through cell ...

Two newly identified disease-causing genes, known as Bzw2 and Eif5a2, have been implicated in early prostate cancer ...

Structural alterations of the genome are commonly observed in human cancer and can contribute to tumorigenesis through a variety of mechanisms including the formation of fusion oncoprotein and changes ...