providing the highest delivery reported so far of an oligonucleotide drug to skeletal muscle. Other types of RNA targets beyond the messenger RNAs (mRNAs) that have been the focus of established ...

In an effort to bolster drug development in this space, researchers at Thermo Fisher Scientific and the European Pharma Oligonucleotide Consortium published a consensus article in February on best ...

Arthur A. Levin, the interviewee, is the Executive Vice President of Research and Development at Avidity Biosciences. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the ...

Mass spectrometry has been growing as the analytical technique of choice to analyze and quantitate oligonucleotide drugs from discovery to QC. Characterization of production related impurities or ...

“Many pharmaceutical companies have rich pipelines of oligonucleotide-based drug candidates that could benefit from an alternative production process. CPI and partners are keen to engage with pharma ...

GSK has set its sights on dominance of the market for hepatitis B virus (HBV) therapeutics, licensing an antisense oligonucleotide drug from Arrowhead Pharma and Johnson & Johnson that had been ...

Therapeutic oligonucleotides are an emerging class of drug molecules that have the potential to treat a wide range of diseases. The finding, by The University of Manchester, will facilitate ...

SMi reports: Workshop Overview for the Oligonucleotide Therapeutics and Delivery Conference, which will convene in London on 15 th September 2020 one day before the conference taking place on the ...

As part of the deal, the duo will leverage Genetic Leap's RNA-targeted AI platform to develop oligonucleotide drugs for ...

Therapeutic oligonucleotides act on different stages of pathological gene expression. Standard schematic of oligonucleotide activities in pathogenesis disease progression. Decoys bind to transcription ...