immunosuppressive features facilitate expansion of the dysplastic clone and can eventually lead to disease progression to acute myeloid leukemia. Various cell types contribute to dysregulation of ...

therefore lysing the AML blast (blue arrow). This lysis is the definitive goal of an immune therapy for AML by using a defined T-cell epitope peptide derived from a LAA. AML: Acute myeloid ...

Medically reviewed by Benjamin Leach, MD Chronic myelomonocytic leukemia (CMML) is a rare cancer that begins in the ...

A subset of patients with myeloproliferative neoplasms (MPNs) -- clonal disorders of hematopoietic stem cells that include ...